ID A0A3P8QW21_ASTCA Unreviewed; 1194 AA.
AC A0A3P8QW21;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Protocadherin 9 {ECO:0000313|Ensembl:ENSACLP00000033748.1};
GN Name=PCDH9 {ECO:0000313|Ensembl:ENSACLP00000033748.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000033748.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000033748.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000033748.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8QW21; -.
DR STRING; 8154.ENSACLP00000033748; -.
DR Ensembl; ENSACLT00000034550.1; ENSACLP00000033748.1; ENSACLG00000022872.1.
DR GeneTree; ENSGT00940000155079; -.
DR OMA; AYKCPLN; -.
DR Proteomes; UP000265100; Chromosome 1.
DR Bgee; ENSACLG00000022872; Expressed in brain and 1 other cell type or tissue.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 7.
DR Gene3D; 2.60.40.60; Cadherins; 7.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR InterPro; IPR013585; Protocadherin.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF248; PROTOCADHERIN-9; 1.
DR Pfam; PF00028; Cadherin; 6.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF08374; Protocadherin; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 7.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 7.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..1194
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017946069"
FT TRANSMEM 811..835
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..141
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 142..251
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 252..357
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 364..468
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 469..571
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 572..674
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 686..796
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 848..880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 983..1020
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1055..1079
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1112..1165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 983..1019
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1142..1157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1194 AA; 131595 MW; D1C939954346E8C7 CRC64;
MDLKDYYLLG ALLACIWLDP SIAQELIYPI REELQENVLI GNIPKDLNIS HTNAATGTSA
NLVYRLVSKA GDNPLVRVLS STGEIFTTSN RIDREKLCPG PSFEDSECSF EIEVVILPND
YFRLIKIKII VKDTNDNAPM FPSPVINISI PENTLINSRF AIPSATDPDT GPNSVHKYEL
INGQSAFGLD IVETPEGEKW PQLIVQQNLD REQKDTYVMK IKVEDGGSPQ KSSTAILQVT
VTDVNDNKPV FKESQIEVHI PENSIIGTSV VQLQATDADI GANAEIHYVF GTQVSPATKR
LFALNATSGL ITVQRPLDRE ETAIHKLSVL ASDGSSSPAR ATVTINVTDV NDNPPNIDLR
YIISPINGTV FLSEKDPINT KIALITVSDK DTDINGKVIC FIEKDVPFHL KAVYDNQYLL
ETSALLDYEG TKEYNFKIVA SDSGKPSLNQ TALVRVRLED ENDNPPIFTQ PVIELAVMEN
NKRDLFLTTL SATDEDSGKN AEIVYQLGPN ASFFDLDRKT GVLTASRVFD REDQDRFLFT
VTARDNGTPP LQTQAAVIVT VLDENDNNPK FTHNHFQFFV SENLPKYSTV GVITVTDSDA
GENAAVSLSI LNDNENFILD PYSGVIKSNV SFDREQQSSY TFDVRAVDSG RPPCSSAAKV
TINVIDVNDN TPIVIYPPSN TSFKLVPLSS IPGSVVAEVF AVDGDTGMNA ELKYTIVSGN
NKGLFRIDPV TGNITLEEKP ALTDIGLHRL VVNISDLGYP KSLHTLVLVF LYVNDTVGNS
TLINDLIRRT METPIDRNIG ESSETYQSGD YLTIMIAFVT GALVVIIVIF VTVLLRCRHA
SRFKAAQRKK QGAEWMSPNT ENKQNKKKKR KKRKSPKNSL LNFVTIEGNK PDDPAHEPIN
GTISLPTELE EQGIGRFDWN ATPTTTFKPS SPDLARHYKS ASPQSAFHLK ADTPVSVKKH
HVIQELPLDN TFVGGCDTLS KRSSTSSDHF SASECSSQGG FKTKGPMHTR QQGTLTRART
ELNPEYLDLR PRAELNPEYW TPCTPLAQDD FYEQASPDKR TEADGNSDPN SDGPLGPRGL
VEATEMCTQE CLVLGHSDNC WMPPTLGTYQ QPKSPVTSFG SQREWGPKDK LLNGHTLSRT
WKNESGRSEH FGDRKQFGSG EGHFTSSGMA DIPLVSLKSC QPASCPDSPK DQQL
//
