ID A0A3P8QWX1_ASTCA Unreviewed; 471 AA.
AC A0A3P8QWX1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Interferon regulatory factor 6-like {ECO:0000313|Ensembl:ENSACLP00000034180.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000034180.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000034180.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000034180.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8QWX1; -.
DR STRING; 8154.ENSACLP00000034180; -.
DR Ensembl; ENSACLT00000034991.1; ENSACLP00000034180.1; ENSACLG00000023143.1.
DR GeneTree; ENSGT00940000157451; -.
DR OMA; MTIFRIP; -.
DR OrthoDB; 3740806at2759; -.
DR Proteomes; UP000265100; Chromosome 5.
DR Bgee; ENSACLG00000023143; Expressed in ovary and 2 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 2.60.200.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR019471; Interferon_reg_factor-3.
DR InterPro; IPR017855; SMAD-like_dom_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF9; INTERFERON REGULATORY FACTOR 6; 1.
DR Pfam; PF00605; IRF; 1.
DR Pfam; PF10401; IRF-3; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SMART; SM01243; IRF-3; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
FT DOMAIN 7..115
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
FT REGION 121..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 471 AA; 53313 MW; FCFAC7718CEF321B CRC64;
MAVTPRRVRL KPWLVAQVES GRYPGLTWLD RENMRFRIPW KHATRHTPQH EDEDTIFKAW
AVETGKFQEG VDEPDPAKWK AQLRCALNKS REFNLVYDGT KEIPMNPWKI YDVCDIPQPL
SNHGSSDAGP WTPGDDDGLE EDIPDTPESL PPYPSNGTPS PLIMWSPMGS ESSMQPPSCP
PSNEVWPKEE PVKPWPKEEP VDVEMQQTTH DMPPVTLPDP SLQPPPLPDG LFASPEMWIS
SLPMTDLEVQ FLYRGKEMCP TATVSNPLGC RLFYGDLGPM VNQEELFGPV NLEQLRFPTT
EHITNDKQRV FTNRLLDVMD RGLILEVSGH DIYAVRLCQC KVYWSGPCAP NPAAPNLIER
QRKVKLFCLE SFLAGVIAQQ RGQAPSTPDY EINLCFGEEW PDGRPKERKL IMVQVIPVVA
RMISELFSSD DNTRSLDSGS IRLQISMENI KDSIVTQLKQ LYCLLQTLVG L
//
