ID   A0A3P8QX19_ASTCA        Unreviewed;      1297 AA.
AC   A0A3P8QX19;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=C-Jun-amino-terminal kinase-interacting protein 4-like {ECO:0000313|Ensembl:ENSACLP00000034230.1};
GN   Name=SPAG9 {ECO:0000313|Ensembl:ENSACLP00000034230.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000034230.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000034230.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000034230.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the JIP scaffold family.
CC       {ECO:0000256|ARBA:ARBA00009866}.
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DR   Ensembl; ENSACLT00000035043.1; ENSACLP00000034230.1; ENSACLG00000023098.1.
DR   GeneTree; ENSGT00940000153496; -.
DR   Proteomes; UP000265100; Chromosome 8.
DR   Bgee; ENSACLG00000023098; Expressed in anal fin and 8 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005078; F:MAP-kinase scaffold activity; IEA:InterPro.
DR   Gene3D; 1.20.58.1770; -; 1.
DR   Gene3D; 1.20.5.1000; arf6 gtpase in complex with a specific effector, jip4; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR039911; JIP3/JIP4.
DR   InterPro; IPR032486; JIP_LZII.
DR   InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR   InterPro; IPR034743; RH1.
DR   InterPro; IPR034744; RH2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR13886:SF2; C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4; 1.
DR   PANTHER; PTHR13886; JNK/SAPK-ASSOCIATED PROTEIN; 1.
DR   Pfam; PF16471; JIP_LZII; 1.
DR   Pfam; PF09744; Jnk-SapK_ap_N; 1.
DR   Pfam; PF19056; WD40_2; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS51776; RH1; 1.
DR   PROSITE; PS51777; RH2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          6..94
FT                   /note="RH1"
FT                   /evidence="ECO:0000259|PROSITE:PS51776"
FT   DOMAIN          563..669
FT                   /note="RH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51777"
FT   REGION          175..397
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          868..903
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          917..951
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          67..161
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          492..591
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          790..817
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        230..330
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        345..363
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        364..384
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        883..902
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        928..951
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1297 AA;  143035 MW;  38F5BE96F010A96E CRC64;
     MELDDVVLYQ DDSGNSTMMS ERVSGLASSI YREFERLIEK YDEDVVKELM PLVVAVLENL
     DSVFAVNQEH EVELELLKED NEQLVTQYER EKALRKNTEE RYIALEDSQD GEKKDLQCRL
     VTLESHTRQL ELKTRNYADQ ISRLEEREAE LKKEYNALHQ RHTEMIHSYM EHLERTKHQH
     AAMTAEPSDT GTSVRTRKER PVSMGLFQLP AAEGMTPDLH REPVDTPSEP WRFNNLSHPR
     SNTSLKDELS QLNCGSSRSN TQTNQGSVSK NGTPVSLQDG GSKSTTPSLG GASKSNTPTS
     NYSNNSQSTT PLSPFDGGST GMSPMSSLGR GSASDVAMES VDTPLKDQET SDGHNKNLDR
     SSGKPESNKN IAAVQEGQQK GPESDTTPLK EDDGADSLEK SEVQAIIEST PELDMDLAGC
     RGTSTPTKGG VENLAFDRNT DSLFEELSSA GNDLIGDVDE GADLLGMGRE VEHLIHENTQ
     LLETKNALNV VKNDLISRVD ELSCEKEVLQ GELNAVTHAK TKLEEKNKEL EEELKKVRAE
     LDEAKQKVKN DNEDDSDVPT AQRKRFTRVE MARVLMERNQ YKERLMELQE AVRWTEMIRA
     SKENPTLPEK KKSSLWQFFS RLFSSSGGGA KKPAAEAPVN VKYNAPTSQI QPSVKKKSST
     LQQLPSDKSK AFDFLNEEAP ADSVVSRREQ KRAQYQQVKA HVQKEDGRLQ AYGWSLPKKY
     KANGGQAESK MKSLPVPVFL RPLDEKDASM KLWCATCVNL SGGKTRDGGS IVGASVFYSD
     VSGPESPKKK VGSQSSLDKL DQELRDQQKE QRHQEELSSL VWICTTTKST TKAVVIDANQ
     PGNILEGFFV CNSHILCIAS VPGARETDYP AGEEVPPNSE VGPVGDGNSS ATSTSSTGGD
     SVLGGITVVG CEAEGVTAVP QTAGKDGEAE SRPAEEATEA TETSAESADQ RESLREIYTE
     HVFTDPLGAQ HKVETPANYS QRESDLLKDG VSLNPSAEEQ DLMREEAQKM SSVLPTMWLG
     AQNGYVYVHS SVAQWKKCLH SIKLKDSVLG IVHVKGRVLV GLSDGTLAIF HRGVDGQWDL
     TNYHLLDLGR PHHSIRCMTV VHDKVWCGFR NKIYVVQPKA MKIEKSFDAH PRKDSQVRLL
     AWDGDGIWVS IRLDSTLRLF HAHTYQHLQD VDIEPYVSKM LGTGKLGFSF VRITALMVSC
     NRLWIGTGNG VIISIPLTEG HAAASASCAG EAAGDKAADA TTQEGTKCML VMSGGEGYID
     FRMGDEDGEM EEAEDAPIKL QPKAERSHLI VWQVTQD
//