ID A0A3P8QYT6_ASTCA Unreviewed; 1072 AA.
AC A0A3P8QYT6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Semaphorin 5A {ECO:0000313|Ensembl:ENSACLP00000034860.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000034860.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000034860.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000034860.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR AlphaFoldDB; A0A3P8QYT6; -.
DR Ensembl; ENSACLT00000035684.1; ENSACLP00000034860.1; ENSACLG00000023501.1.
DR GeneTree; ENSGT00940000158036; -.
DR Proteomes; UP000265100; Chromosome 9.
DR Bgee; ENSACLG00000023501; Expressed in brain and 4 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0022008; P:neurogenesis; IEA:UniProt.
DR CDD; cd11263; Sema_5A; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 6.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR042821; Sema5A_sema.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF78; SEMAPHORIN-5A; 1.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF00090; TSP_1; 5.
DR PRINTS; PR01705; TSP1REPEAT.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SMART; SM00209; TSP1; 6.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 6.
DR PROSITE; PS51004; SEMA; 1.
DR PROSITE; PS50092; TSP1; 6.
PE 4: Predicted;
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..1072
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018272053"
FT TRANSMEM 972..994
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 43..492
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
SQ SEQUENCE 1072 AA; 119793 MW; 435AF67282BC8E02 CRC64;
MGRPVIQHAL LLLQCMLVLR PGGVAGRRGP VLLPESPCYR TEHPLVPHSE MEPWIFRFKA
EGTVDYSQLT FDPGQNELIV GARNHLFRLN LEDLTLIQEA EWHCDEFTKG ACFSRGKSEE
ECQNYIRVLL VNGNRLFTCG TNAFTPICTN RTLTNLTEIH DQISGMARCP YNPLHNSTAL
ITSSGELYAA TAMDFSGRDP AIYRSLGGLP PLRTAQYNSK WLNEPNFVSS YDIGNFTYFF
FRENAVEHDC GRTVFSRAGR VCKNDIGGRF LLEDTWTTFM KARLNCSRPG EIPFNYNELQ
GTFYLPELEL LYGIFTTNVN SIAASAVCAF NLSAISQAFN GPFKYQENSR SAWLPYPNPN
PDFQCGTIDS GAYVNLTQRN LQDAQKFLLM HEVIQPVVPV PYFMEDNVRF THVAVDVVQG
KDTLFHIIYL ATDYGTIKKV LSPLNQSTGS CLLEEIELFP PRKRQHIRSL LILHSRSELY
VGVRDQVIKI PLKRCSYHKS REACVGARDP YCGWDLLLKK CTTLEESIRM SQWEQSISKC
PVRNVTVDGG FGAWSGWSTC SHNDGGSAGS CLCRTRACDN PAPQCGGQQC HGISVEVANC
SRNGAWTPWT SWSPCSTTCG IGFQVRQRSC SNPTPRHGGR VCVGQNREER YCNEHLPCPP
HVYWSAWSAW ERCTVPCGGG IQSRRRTCEN GNDCPGCGQE YQSCNTLPCP DLKKTTPWTP
WTPVNISDNG GHYEQRFRYT CKARIPDPSL LEVGRQRIEM RYCSSDGSTG CSTDGEVLRL
GRISSHTVNG AWSSWSSWSQ CSRDCSRGIR SRKRTCSNPE PRYGGQTCLG PAQEYQECNI
TPCPVDGSWS CWSSWSKCSV TCGGGHYMRT RTCSNPLPAY GGDICLGLHT EEALCNTQPC
PESWSSWSEW SHCDSSGAQL RVRHCDVLFP TGNQCLGNSS ETRPCSPDSN FIPEVSIARS
SQEERRCGDF NLFHMIAVGL SSSILGCLVT LLVYSYCQRY QQQSHDATVI HPISAAPLNT
SITNHINKLD KYDTVEAIKP DVSVLLPLDD PAMHQPLSSN MGVSMRGLEI FY
//
