ID   A0A3P8QZ84_ASTCA        Unreviewed;       877 AA.
AC   A0A3P8QZ84;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=B30.2/SPRY domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000034306.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000034306.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000034306.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8QZ84; -.
DR   STRING; 8154.ENSACLP00000034306; -.
DR   Ensembl; ENSACLT00000035126.1; ENSACLP00000034306.1; ENSACLG00000023236.1.
DR   GeneTree; ENSGT01100000263487; -.
DR   OMA; THIKHEK; -.
DR   Proteomes; UP000265100; Chromosome 3.
DR   Bgee; ENSACLG00000023236; Expressed in anal fin and 5 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd16040; SPRY_PRY_SNTX; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 4.
DR   SMART; SM00589; PRY; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          67..201
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   DOMAIN          680..877
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
SQ   SEQUENCE   877 AA;  98534 MW;  9C9208933D65A01C CRC64;
     IAKAGNPTLL NQIYTELYIT EGGTAEVNDE HEVRRIETAS RKPDNLECTI RQEDIFKASP
     GRDEPIRTVL TKGVAGIGKT VLTQKYTLDW AEDKANQDIQ FMFPFTFREL NVLKEEKFSL
     VELVHHFFTE TKEAGICSFE DFQVVFIFDG LDECRLPLDF HKTTIITDPR KSTSVDVLLI
     NLIRGKLLPS ARLWITTRPA AANQIPPDCV DVVTEVRGFT DPQKEEYFKK RFRDKKQAKI
     ILSHIKTSRS LHIMCHIPVF CWITATVLED VLKTREEGQL PKTLTEMYIH FLVVQAKVKT
     VKYDGGAETD PHWSPESRKM MESLGKLAFD QLQKGNLIFY ESDLTECGID IRAASVYSGV
     FTQIFKEERG LYQDKVFCFI HLSVQEFLAA LHVHLTFINS GLNLLEEQKT TFQKSERSES
     VEKHFYQSAM DKALQSPNGH LDLFLRFLLG LSVQINQSLL RGLLTLTGSS SQTIKKTVQY
     IKEKLSENLP AEKSINLFHC LNELNDCSLV EEIQQSLKAE RLSTNELSPA QWSALVFILL
     SSEEDLDVFD LKKYSASEEA LLRLLPVVQA SNQALLSGCN LSERSCKALS SVLSSQSSNL
     RELDLSNNNL QDSGVKILST GLKSLCCTLE TLRLSGCLIT EEGCTSLASA LSSNPSHLKE
     LDLSYNQPGL SGLKLLSAGL MDPSWRLDTL RYGEKNSCQL TIDTNTVNTN LKLSDNNRTL
     THVDEIQSYP DHPGRFDQLP QVLCRNGLTG RCYWEVEWRG GVLISVSYTG IRRKGNSKDV
     VFGWNDQSWC LYCSDDGPDS VRHNNKGTSI IAAASSSSVS NRVAVYVDCP AGTLSFYRVS
     SDTLIHLHTF NTTFTQTLYP GFRVYPGCSL KVCVVEA
//