ID A0A3P8R8Y7_ASTCA Unreviewed; 240 AA.
AC A0A3P8R8Y7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000037969.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000037969.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8R8Y7; -.
DR Ensembl; ENSACLT00000038856.1; ENSACLP00000037969.1; ENSACLG00000018977.1.
DR GeneTree; ENSGT00950000183127; -.
DR Proteomes; UP000265100; Unplaced.
DR Bgee; ENSACLG00000018977; Expressed in spleen and 8 other cell types or tissues.
DR GO; GO:0042613; C:MHC class II protein complex; IEA:InterPro.
DR GO; GO:0019882; P:antigen processing and presentation; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR014745; MHC_II_a/b_N.
DR InterPro; IPR000353; MHC_II_b_N.
DR PANTHER; PTHR19944:SF106; DLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR-1 BETA CHAIN-LIKE-RELATED; 1.
DR PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00969; MHC_II_beta; 1.
DR SMART; SM00407; IGc1; 1.
DR SMART; SM00921; MHC_II_beta; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..240
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017967771"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..185
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 240 AA; 27312 MW; 4145F8C98386C3CF CRC64;
MASSFLCLSL LFISFSTADG FKMFVVSRCV FNSTELKDIE YIQSYYYNMM EILRFDSNVG
EYVGYTEYGV NAGCMESSEG DVLPTQHWWL LQQPSPYVKL HSTTPAYSQH PAMLVCSVYD
FFPSKIKVNW LRDGQEVTSD VTSTEEMADG DWYYQTHSHL EYTPRSGEKI SCKVEHASLE
KPLITDWDPS SSMPESERNK LAIGASGLIL GLILSLAGFI YYRRKARGQS RTPTHRPVHT
//
