ID   A0A3P8RAN1_ASTCA        Unreviewed;       649 AA.
AC   A0A3P8RAN1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=G2/M phase-specific E3 ubiquitin-protein ligase-like {ECO:0000313|Ensembl:ENSACLP00000038127.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000038127.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000038127.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000038127.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00104}.
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DR   AlphaFoldDB; A0A3P8RAN1; -.
DR   Ensembl; ENSACLT00000039015.1; ENSACLP00000038127.1; ENSACLG00000025760.1.
DR   GeneTree; ENSGT00950000182865; -.
DR   Proteomes; UP000265100; Chromosome 17.
DR   Bgee; ENSACLG00000025760; Expressed in ovary and 2 other cell types or tissues.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR   InterPro; IPR000569; HECT_dom.
DR   InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR   Pfam; PF00632; HECT; 1.
DR   SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR   PROSITE; PS50237; HECT; 1.
PE   4: Predicted;
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW   ECO:0000256|PROSITE-ProRule:PRU00104}.
FT   DOMAIN          574..622
FT                   /note="HECT"
FT                   /evidence="ECO:0000259|PROSITE:PS50237"
FT   REGION          52..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..70
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   649 AA;  73148 MW;  18DE15CA4CD23BAB CRC64;
     MACGKKPVSL VIKENIEMKV FSSKEPCKVL ITQEEEEEYS VHQRYMASPL FSNSEEAPEQ
     QVQTQPRHQA ETDSPDQEEP HCSAVVCKQE VEIELEPYSN KAGHLKWKRL IPQKKSLVVK
     DVVCLPRGHS MSQLDRQIVP KNKDQAALEA MMMTARITID HSWSATQVKG RLAMLFQGHF
     VKQAGQKFSF TYLQCVQSSR VLFVPDTPSE GWTGEQVLRI SEHGALYILS HHDYSETESE
     GSASETLVVK STDSCQDGKS ELIIKPSICR DTKKSTVDLD TILRAFRQEN VDPGLKTHIQ
     VRRTDLLHGA LEVVRRPDFC FRATPVISFS GEEPDSHEAP VREFFRLMLL ELQHSCVFEG
     LPGSLFMTCN FTALEERKYY EAGVLIGWSL AQGGPGLCCL HPALYQVMCC HSITLEDFNW
     RDIIDTEVQI QLKELHSCTD VKLLSPSLCD WVSRCGIPEI CSANSDEMPA IYSRLVKHYI
     YDRVTKMISQ FTEGLNSCGG LWDMVQSHWE IFAPVMTSAP QQPLSLEEFK QLFTISFSTS
     DAQLRADEEA TAGHWETILT LVRDGKAEFS FEDLLTFITG ADRLPPLGFP RFISLCFYSQ
     DASMQDLRLP HAASSSLELY LPRGVAGAVD LLALLNRAVH KVLRDGEDN
//