ID A0A3P8RDB1_ASTCA Unreviewed; 518 AA.
AC A0A3P8RDB1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Tubulin-specific chaperone E {ECO:0000256|ARBA:ARBA00015004};
DE AltName: Full=Tubulin-folding cofactor E {ECO:0000256|ARBA:ARBA00030180};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000039057.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000027185.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000039057.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TBCE family.
CC {ECO:0000256|ARBA:ARBA00006286}.
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DR STRING; 8154.ENSACLP00000027185; -.
DR Ensembl; ENSACLT00000027821.1; ENSACLP00000027185.1; ENSACLG00000018483.1.
DR Ensembl; ENSACLT00000039985.1; ENSACLP00000039057.1; ENSACLG00000026359.1.
DR GeneTree; ENSGT00530000063405; -.
DR OMA; NENSTFA; -.
DR OrthoDB; 11880at2759; -.
DR Proteomes; UP000265100; Chromosome 6.
DR Bgee; ENSACLG00000018483; Expressed in anal fin and 4 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR CDD; cd17044; Ubl_TBCE; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR044079; Ubl_TBCE.
DR PANTHER; PTHR45617:SF78; 2MIT, ISOFORM B; 1.
DR PANTHER; PTHR45617; LEUCINE RICH REPEAT FAMILY PROTEIN; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF14560; Ubiquitin_2; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
DR PROSITE; PS51450; LRR; 1.
PE 3: Inferred from homology;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 30..74
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
SQ SEQUENCE 518 AA; 57686 MW; ED51174A27ECD0F1 CRC64;
MGVDEAEVPV DAVGKRVSCG GERATVRYFG PVPPTAGLWL GVEWDNPDRG KHDGSHEGVQ
YFTCRHPTGG SFVRPAKVSF GVDYLTAVRQ EYKIDSEEVL SEEISISKKK LKWGNIKERG
FESLPSVLLS RSDVSWSGAD GEIRTTTPNV EWLDLTGTLM SCWEDVATIS QQLDRLEGLQ
LSYNRLRLPP DPSALRHAFS ALKVVVLNGC QLTWPQILEC APMWPQLEDL CVEENSITEL
QRPEGLLQSL KSLSLSSNPL VQDSVLSLSA LPRLEQLNLS KTGLSVIQFE DAAPGSHTAA
YAALKNLNLD HNSITEWFVV NELAKLPSLV RLSCRGNKLV SRDGNPKTAN QMLIAKLGQL
VVLNSCEIHA DDRRGAELDY IKMFGEEWLK AGGRSQPSPQ FICEHPRYQA LISKYGAPEE
GELRKPEPFA LKNQLLKITF VFPDDANRKP LEKKLPASMV VQKVKGLLYR LLKVPAADLR
LTYTSPKMVG TEFEIDSDLK TLQFYSIEDG DQVLVRWS
//
