ID   A0A3P8REA5_ASTCA        Unreviewed;      1115 AA.
AC   A0A3P8REA5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=ELKS/RAB6-interacting/CAST family member 1 {ECO:0000313|Ensembl:ENSACLP00000039412.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000039412.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000039412.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000039412.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   AlphaFoldDB; A0A3P8REA5; -.
DR   Ensembl; ENSACLT00000040346.1; ENSACLP00000039412.1; ENSACLG00000026518.1.
DR   GeneTree; ENSGT00650000093320; -.
DR   Proteomes; UP000265100; Chromosome 7.
DR   Bgee; ENSACLG00000026518; Expressed in brain and 7 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0098793; C:presynapse; IEA:UniProt.
DR   Gene3D; 1.10.287.1490; -; 1.
DR   Gene3D; 1.20.5.2440; -; 1.
DR   InterPro; IPR019323; ELKS/CAST.
DR   InterPro; IPR037245; FIP-RBD_C_sf.
DR   InterPro; IPR019018; Rab-bd_FIP-RBD.
DR   PANTHER; PTHR18861; ELKS/RAB6-INTERACTING/CAST PROTEIN; 1.
DR   PANTHER; PTHR18861:SF1; ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1; 1.
DR   Pfam; PF10174; Cast; 1.
DR   Pfam; PF09457; RBD-FIP; 1.
DR   SUPFAM; SSF144270; Eferin C-derminal domain-like; 1.
DR   SUPFAM; SSF90257; Myosin rod fragments; 1.
DR   PROSITE; PS51511; FIP_RBD; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   DOMAIN          1045..1107
FT                   /note="FIP-RBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51511"
FT   REGION          1..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          269..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          339..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          783..834
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          173..200
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          408..435
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          499..663
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1061..1088
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        17..33
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1115 AA;  127330 MW;  E35D8C2C1AD29EB0 CRC64;
     MYGSARSVGR GDTNHSGGRD GSGTGNQGSG RSPRLPRSPR MGHRRTNSTG GSGGGPGGAG
     GKTLSMENIQ SLNAAYATSG PMYLSDNEVT MGGDHLPKTG GTVTTMGRQR VTYGSRGSSS
     GVVAASTPNI STTVPANAVL PAGMMAGDAL AFGDHHMAST VPHSLRQARD NTILDLQAQL
     KEVLRENEML RREVEVKESK LSSSMNSIKT FWSPELKKER ALRKDEASKI AVWKEQYRVI
     QDEAQHLQMT VQALQDELRI QRDLNQLLQQ DPASQGRDLA LTSEPTEENY RRLQGEHERQ
     AKELFLLRKT LEEMELRIDT QKQTLAARDE SIKKLLEMLQ SKGPSAKASE EDQERTRRLA
     DAEMHRHHLE SLLDQRDREI TALREQELHR RYEGTPESTK TKALQTVIDM KDAKINSMER
     SLRDMEEELL MLKSNGLLSC EERQEEMKQM EVYRSHTKFM KNKMEQVKQD LSRKDTELLG
     LQTKLETLTN QFSDSKQHIE VLKESLTAKE QRAAILQTEV DALRLRLEEK EATLNKKSKQ
     IQEMSEEKGT LNGEIHDLKD MLEVKERKIN VLQKKIENLQ EQLRDKEKQM SSLKERVKSL
     QADTSNTDTA LTTLEESLAE KERIIERLKE QRDRDDREKT EELECTKKEL KELKERLSLL
     QGDLSDRETS LLDLKEHASS LASSGLKKDS RLKSFEIALE QKKEECLKLE NQLKRAQNAA
     LEAQANTELA ERIRNLEQEV ARHREDSGKA QAEVDRLLEI LREMENEKND KDKKISELES
     LASRQMKDQS KKVASLKHKE QVEKSRNARL MEEARKREDN LSENSQQVKD TLRQKTERIE
     ELEEALRESV QITAEREMVL AQEEAARSLQ EKQMEELLGA MEKVKQELES MRAKLASTQQ
     SLCEKEAHLT TLRAERRKHL EEVLEMKQEA LLAAISEKDA NIALLELSSS KKKKTQDEVA
     QLKREKDRLV QQLKQQTQNR MKLMADNYED DHLKTAPDQT NHKPSPDQMI PPLLALSQNR
     SKLKLYIAHL TDLCHDRDPS ILSQLTPPAH YHHSDPEDWE EDLQKMSAEQ LERELEVCEK
     ESGELQEYAN SVLQQIADYC PDILEQVVNA LEESC
//