ID   A0A3P8RJ09_AMPPE        Unreviewed;       521 AA.
AC   A0A3P8RJ09;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Protein arginine methyltransferase 3 {ECO:0000313|Ensembl:ENSAPEP00000000186.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000000186.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000000186.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000000186.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8RJ09; -.
DR   STRING; 161767.ENSAPEP00000000186; -.
DR   Ensembl; ENSAPET00000000191.1; ENSAPEP00000000186.1; ENSAPEG00000000139.1.
DR   GeneTree; ENSGT00940000156825; -.
DR   OMA; DGWAVWF; -.
DR   Proteomes; UP000265080; Chromosome 1.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR049482; ANM3-like_C2H2_Zf.
DR   InterPro; IPR025799; Arg_MeTrfase.
DR   InterPro; IPR041698; Methyltransf_25.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   PANTHER; PTHR11006; PROTEIN ARGININE N-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR11006:SF114; PROTEIN ARGININE N-METHYLTRANSFERASE 3; 1.
DR   Pfam; PF21137; ANM3_C2H2_Zf; 1.
DR   Pfam; PF13649; Methyltransf_25; 1.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51678; SAM_MT_PRMT; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW   ProRule:PRU01015}; Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01015};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU01015}.
FT   DOMAIN          70..116
FT                   /note="Protein arginine N-methyltransferase 3-like C2H2
FT                   zinc finger"
FT                   /evidence="ECO:0000259|Pfam:PF21137"
FT   DOMAIN          249..322
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13649"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          128..166
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..26
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..166
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   521 AA;  58570 MW;  0244016E983EF8F2 CRC64;
     CFMLTDGDGA ADEMPELSDE EDNEEDEEQW QWMEEDSQPV TCLFCHRSLS SVAATLQHCT
     AEHQVNLVDV IRKHSLDDYG YIKMINFIRS TKCDASCLTG LPDAPLPWES EDFLRPVLQD
     DPLLQTDPEE LCSSEGSCPS SGPNPHDALL QRAQAAEERA RRSEEAMARA MDDLHKLKLL
     AQGLVLNAET SKSGNLGAVA ELREDEDEAY FSSYGHYGIH EEMLKDKVRT ESYRDFMYRN
     PEVFREKVVL DVGCGTGILS MFAARAGAKK VIAVDQSEII YQAMDIVRSN QLEDKITLIK
     GRIEDIKLPV EKVDIIISEW MGYFLLFESM LDSVLYARDL YLADGGSVYP DLCNISLAAV
     GDTQKHQERI AFWDDVYGFN MGCMKKAVVP EAVVEVVKAE TLISESTVIQ TFDCNSVCLS
     ELEFASDFCL KITNTTECTV SNTHADTTLV KYRTVSVMFS TGPQVTKTHW KQTVFLLEKP
     VSVQAGEELK GKITVRKNKK DPRSLLVTFD VQDRKQTYSL Q
//