ID   A0A3P8RKD1_AMPPE        Unreviewed;       700 AA.
AC   A0A3P8RKD1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Nucleolar protein 9 {ECO:0000313|Ensembl:ENSAPEP00000000517.1};
GN   Name=NOL9 {ECO:0000313|Ensembl:ENSAPEP00000000517.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000000517.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000000517.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000000517.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
CC       {ECO:0000256|ARBA:ARBA00011003}.
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DR   AlphaFoldDB; A0A3P8RKD1; -.
DR   STRING; 161767.ENSAPEP00000000517; -.
DR   Ensembl; ENSAPET00000000530.1; ENSAPEP00000000517.1; ENSAPEG00000000416.1.
DR   GeneTree; ENSGT00940000153668; -.
DR   OMA; KEKPYRR; -.
DR   Proteomes; UP000265080; Chromosome 8.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; IEA:InterPro.
DR   GO; GO:0000448; P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:Ensembl.
DR   GO; GO:0060216; P:definitive hemopoiesis; IEA:Ensembl.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0031017; P:exocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0061113; P:pancreas morphogenesis; IEA:Ensembl.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR045116; Clp1/Grc3.
DR   InterPro; IPR032319; CLP1_P.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12755; CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; 1.
DR   PANTHER; PTHR12755:SF3; POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9; 1.
DR   Pfam; PF16575; CLP1_P; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          327..459
FT                   /note="Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop"
FT                   /evidence="ECO:0000259|Pfam:PF16575"
FT   REGION          1..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        71..94
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   700 AA;  77017 MW;  CA414BA4B690B49B CRC64;
     MKVNKNTQAR SKSQKWKDVR GKRCRPPISS SDINSSPVMA RMIKEHQVSV KKKPSVKRLK
     NRAKPVSDPK ITPPQSGSKK SYTQANGSSV FNLDKESDDS QEWKEYSQLI HKNGVETSDD
     VEVGQPGRLE GEALHQCAQR DDRQNRAVLI MQKDQTLCFR GKCFLTCLYG RVEVMGFTIE
     EGQQSYPLFS PASHCPLTIR ALQSSDDSRN NRTRASHILQ KYLTGAPRKK LLKNLTSSST
     IILLEPMETP LTRFLSSFTD LSELFSPPVS ELMSAVLDTP LNGLGMIPLT SMIEGLKMPK
     SYQDALNTVV NACRGDMDGC AVILVCGTKN VGKSTFIRLL INTLLNHTAS VDYLEGDLGQ
     TEFTPAGCLS LGTITEPLLG PPFTHQHTPE HMIYYGQSSC ESDLDRYLES LKSLWHRRCQ
     SRETPVVINT MGWVKGFGFQ LLVDMIRFFP VSHVVQLSHG GVSQCAALTP EFLRTAHGFQ
     THPPAQTALD EFTESHSPPR SYSHLAVQSE FQGVGRQGTA KHQRTNEHRE LSLLAYLSQL
     QSSDPGPVRP LHSLTPYQVP NTAVALGVIH CEVVPTHMLY AANASLVGLC CLSEKVASRG
     GPVLLSQAPI CPCVGLGVLR GIDVARGLYY VLTPVDPAVL RKVNCLLLGA ISLPSCILTS
     QPGVEGERPY VTTDYSFDLT GAGKLRVFKG LMRPSQVGMQ
//