ID   A0A3P8RM49_AMPPE        Unreviewed;      1532 AA.
AC   A0A3P8RM49;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=VWFD domain-containing protein {ECO:0000259|PROSITE:PS51233};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000000349.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000000349.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000000349.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   Ensembl; ENSAPET00000000357.1; ENSAPEP00000000349.1; ENSAPEG00000000256.1.
DR   GeneTree; ENSGT00940000156076; -.
DR   OMA; LVCESPM; -.
DR   Proteomes; UP000265080; Chromosome 1.
DR   CDD; cd19941; TIL; 3.
DR   Gene3D; 2.10.25.10; Laminin; 2.
DR   InterPro; IPR036084; Ser_inhib-like_sf.
DR   InterPro; IPR002919; TIL_dom.
DR   InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR   InterPro; IPR001007; VWF_dom.
DR   InterPro; IPR001846; VWF_type-D.
DR   InterPro; IPR025155; WxxW_domain.
DR   PANTHER; PTHR11339; EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED; 1.
DR   PANTHER; PTHR11339:SF404; MUCIN-5AC; 1.
DR   Pfam; PF08742; C8; 3.
DR   Pfam; PF13330; Mucin2_WxxW; 2.
DR   Pfam; PF01826; TIL; 1.
DR   Pfam; PF00094; VWD; 4.
DR   SMART; SM00832; C8; 3.
DR   SMART; SM00215; VWC_out; 2.
DR   SMART; SM00216; VWD; 3.
DR   SUPFAM; SSF57567; Serine protease inhibitors; 4.
DR   PROSITE; PS51233; VWFD; 3.
PE   4: Predicted;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          10..216
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          313..481
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          757..920
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   REGION          1086..1154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1260..1354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1464..1507
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1532 AA;  164730 MW;  399E94C8D3AC477F CRC64;
     NSVSPAHNGQ VCSTWGNFHY KTFDGDIFQL HSTCNYILTS SCHSTYNDFN IQIRRQEAGG
     SSTIKNIILN LQGAVVELFL NFCKNMTLNI IRFFTQVLTV ELDQKFKNLT CGLCGDFNGV
     QLHDEFYSHG THRPTLEHQS ICDNLILMGP AFSSCHNLLD ITSFTSACVA DLCHCANSEG
     EKADPLCLCN TVSEFSRQCV HAGGKPQNWR TKELCWKSCQ YQMEYKECGS PCADTCSNPD
     ASLTCDSHCM DGCFCPAGTV FDDLNRRGCV PLSECSCSYN SKTYGPGESY SSNCKKCVCN
     SGQWECQEED CPGTCSVEGG AHIKSFDGKF YTFHGDCSYV LAKDCSGTQF VIQGELVQCG
     MTESETCLKS VTLGLSGGAN VSVIHKKSPT HNTVYLPGIS AFRASSYYLL VQTSVGALLE
     VQLEPVMQLY ITVTSDHQAN TCGLCGNFNS NQADDFLKLS GVTDATAAGF ANSWKTHAGC
     PDVKSSFKNP CSLSVDNENY AEHWCSMLTD PQGVFASCHS EISPDSYKEN CMYDSCNCEK
     SEDFMCAAVS SYIHACAAAG IKISDWRKVI CGKYASSCPS GMVYSYNITS SSRTCRCIGS
     TDLSCHSFPP IDGCICAEGT YMDDSGKCVP SEACPCYNEG SAVPAGQVIN KEGVMWYENT
     CAPPMVFFNC SANGPAAKGT ECEKSCSYLQ VSTGCVSGCM CASGLVSDGN GGCIESGNCS
     CVHNGISYQP GETTKVDCNT CTCNGRTWQC TTNQCDGTCY VYGDGHYMTF DQNRFTFDGS
     CEYILTQSNG TFRVITENVP CGTTGTTCSK TIKIFLGNAE LILTDGSYQL LSSGAAEAAP
     FQYSTMGNYL VVEANNGLIL MWDKKTTLLI KLSPKYKGHV CGLCGNYDGS ANNDLTTRSN
     AVVVNPLVFG NSWKDLSSCP NAQNITSPCT SNPYRQSWAQ KQCSIIQSDV FSACHSSVDP
     VPYYDACVFD SCACDTGGDC ECFCTAVAAY AESCNQAGVC VQWRTPNICP VFCDYYNPPD
     ECEWHYMPCG SPCMKTCRNP SSNCSTQIPP LEGCYPKCPP AVPYFDEDTM TCVSKEQITT
     HPTTTTTITA TPTTTTTQPP TTTITTTPTA TQPPTTTATT TTPTTTETTS TTQPPTTTTT
     TTTPTTTMTT QPTTTCPGGH DVVCDWSNWI NLGSPTPGPD GGQNDTIQNI ISAGYHICSS
     PEEVQCRAVL YPELSMSQLG QAVTCNKDVG LICINKQQGL NQECFDYEIK FKCCGCPRTS
     STTVTTTTPT TTTPTTTEPK TTTHLPTTTA TTTTPTTTTT QPPTTTATTT PTTTETTITT
     TSTTTTPTTT TTQPPSTTAT TTRPTTTMTA QPTTTCPGGH DVVCDWSNWI NLGSPKPGPD
     GGQNDTIQNI ISAGYHICSS PEEVQCRAVL YPELSMSQVG QAVICNKDVG LVCINKQQGL
     QQKCFDYEIR FKCCGCPTTH VPTTTPTTTT PSTTETTTTT HLPSTTTAIS STNPATTSEL
     NPVTGRTSTP VTKPLICHCL HNGTTFHPGK YG
//