ID   A0A3P8RT42_AMPPE        Unreviewed;       641 AA.
AC   A0A3P8RT42;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=RNA polymerase II-associated protein 3 {ECO:0000256|ARBA:ARBA00040133};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000003813.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000003813.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000003813.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the RPAP3 family.
CC       {ECO:0000256|ARBA:ARBA00038275}.
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DR   AlphaFoldDB; A0A3P8RT42; -.
DR   STRING; 161767.ENSAPEP00000003813; -.
DR   Ensembl; ENSAPET00000003907.1; ENSAPEP00000003813.1; ENSAPEG00000002745.1.
DR   GeneTree; ENSGT00940000156749; -.
DR   OMA; NFTPDRP; -.
DR   Proteomes; UP000265080; Chromosome 21.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR025986; RPAP3-like_C.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR001440; TPR_1.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR46423; RNA POLYMERASE II-ASSOCIATED PROTEIN 3; 1.
DR   PANTHER; PTHR46423:SF1; RNA POLYMERASE II-ASSOCIATED PROTEIN 3; 1.
DR   Pfam; PF13877; RPAP3_C; 1.
DR   Pfam; PF00515; TPR_1; 1.
DR   Pfam; PF13181; TPR_8; 2.
DR   SMART; SM00028; TPR; 6.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50005; TPR; 4.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}.
FT   REPEAT          135..168
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          203..236
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          288..321
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          356..389
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   DOMAIN          521..612
FT                   /note="RNA-polymerase II-associated protein 3-like C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13877"
FT   REGION          35..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          112..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          248..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          485..526
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        72..88
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        252..266
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        268..283
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        496..510
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   641 AA;  72825 MW;  7B1A049B4E936122 CRC64;
     MSVGNKAVEL QLQMRQNAED LHSFMKEMES WETDIKRRDE ELRTGGAQEV QKNLPPVRNK
     DYKKKKREKK KKTELSGNGD AKVEETKRAS RIKAYDYRSW DKFDVDKALE EMDNEECHES
     NESDSEEAAV DQEKALAEKE KGNKFFKDGK YDEAIECYTR GMGADPYNPV LPTNRATSFF
     RLKKYAVAES DCNLAIALDG NYVKAFARRG AARVALKKYE SALEDYETVL KLDPGNVEAQ
     NEVKKIKEET SGHQAATVQS EATLQEEAPT VDPDKQRLVE DQQRRQEAVL QKDRGNAYFK
     EGKFEAAVEC YTRGMEADSM NVLLPANRAM AFLKLEKYRE TEEDCTKAIS LDSTYSKAFA
     RRATARVALG KLEEAKQDFQ QLLKLEPGNK QALNELQKLQ IDSTGLLQTE ESSLQRTVQP
     IDKPEHLRST KPLRRINVEE ISGKVTLPES VVQEVMKETE DGSSPLSTSP SAKIIKLEAI
     SGSPSLTSDQ FPASKPTKEA TKEEIVRPVE PSTTETELPP PPTNSFQLEA DFRKIRKQPQ
     VIYRYLRQIT PEAYAKIFHN SLEPDILNQI LRTMQEFYIK NEAPAVTMET LSSLASVRRF
     DMAVMFMSSS EKKVLKELFD FLHRAELDRS SIAALQKKYG V
//