ID   A0A3P8RWF3_AMPPE        Unreviewed;       484 AA.
AC   A0A3P8RWF3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAPEP00000003574.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000003574.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000003574.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000003574.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3P8RWF3; -.
DR   Ensembl; ENSAPET00000003657.1; ENSAPEP00000003574.1; ENSAPEG00000002526.1.
DR   GeneTree; ENSGT00940000158414; -.
DR   Proteomes; UP000265080; Chromosome 10.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.3590.10; acid-sensing ion channel 1 domain; 2.
DR   Gene3D; 1.10.287.820; Acid-sensing ion channel domain; 1.
DR   Gene3D; 1.10.287.770; YojJ-like; 2.
DR   InterPro; IPR001873; ENaC.
DR   InterPro; IPR004724; ENaC_chordates.
DR   InterPro; IPR020903; ENaC_CS.
DR   NCBIfam; TIGR00859; ENaC; 1.
DR   PANTHER; PTHR11690:SF252; ACID-SENSING ION CHANNEL 1C; 1.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
DR   PROSITE; PS01206; ASC; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Ion channel {ECO:0000256|ARBA:ARBA00022461};
KW   Ion transport {ECO:0000256|ARBA:ARBA00022461};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022461}.
SQ   SEQUENCE   484 AA;  55176 MW;  217D5FF1C548A87E CRC64;
     MKGSSEESIE SVRPSNLQAF ANISTLHGMS HIFAYGHMTF RRFLWTLSFL GSLSLLMLVC
     MDRVSYYLEY PHVTKLDEVA ATNLTFPAVT FCNLNEFRFS KITRNDLYHV GELLALLNNN
     YQIANPHLAE PEVLAALKDK ANFQNFKPKL FNMTDFYNRT GHDINDMLLQ FRGETCTYKN
     FSTIYTRYGK CYTFNSGLDG NPLLTTLKGG TGNGLEIMLD IQQDEYLPVW GETDETSYEA
     GIKVQIHSQD EPPFIDQLGF GVAPGFQTFV SCQQQLLQYL PPPWGDCKST PIDSEYFSTY
     SITACRIDCE TRYLLENCNC RMVHMPGTST VCTPEQYKDC ADPALDFLVE KDNDYCVCQT
     PCNMTRYGKE LSMVKIPSKA SAKYLAKKFN KSEQYIGENI LVLDIFFEAL NYEKIEQKKA
     YELAGLLGDI GGQMGLFIGA SVLTILEIFD YLYEVFKDKV LGYFIRKKRP QRCQSDNLVI
     FLSL
//