ID   A0A3P8RZU0_AMPPE        Unreviewed;       782 AA.
AC   A0A3P8RZU0;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000004739.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000004739.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000004739.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8RZU0; -.
DR   Ensembl; ENSAPET00000004864.1; ENSAPEP00000004739.1; ENSAPEG00000003363.1.
DR   GeneTree; ENSGT01070000253760; -.
DR   Proteomes; UP000265080; Chromosome 22.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 4.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT   DOMAIN          79..213
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   782 AA;  89357 MW;  83788087E92160FB CRC64;
     MSLRRRCEHV TEGSDEAGGG TLLNRIYTEL YITEGHSGEA DVQHEVMHLE TASKKSLHDT
     PIRCQDIFKA LPEQQRAIRV VLTNGVAGIG KTFSVLKFTL DWAEDRENQD VSVVVVLPFR
     ELNLIRDEQH SLLTLLHVFH PTLQKVTAEQ LAVCKLLFIF DGLDESRLSL DFTNREVVSD
     VSQKSSLDVL LVNLMEGNLL PSTLVWITSR PAAANQIPPK HVDRLTEVRG FTDGQKEEYF
     RRRISDEERS STIISHMKTS RNLHIMCRLP VFCWITAAVL EHMLTTEQRG ELPKTLTDMF
     SHFLLVQTQR KKNKYHEGPE TSPQELTEAD REVLLKLGRL AFEHLQKGNI MFYQEDLEQC
     GLDVTEASVF SGVCTHIFRR ECVMFQKPVY CFVHLSIQEF LTAVYMFHCY TNRNTEVLKK
     FVGEDYGYMS LDVFLKRVLE KSLRSRNGHL DLFVRFLHGL SLESNQRLLK GLLGQTENSP
     EIIRKITNHL KEKKTNISPD RSINMFHCLM EMKDLSVHQE IQEFLQSENR SEKKLSGIHC
     SALAYILQMS EEVLDELDLK KYNTTKQGRL RLIPAVRNCR KARLSGCELS ETHCEAVASA
     LKSNPSHLKH LDLSENKLQD SGMKHLCGFL ENPYCSLKTL RLESCKLSEI SCDSLNSALK
     SNPSHLEYLE LSFNQLQDSG VKHLSGFLEN PDCSLKTLRE QMHLTCVCLE QTFFHCLFRL
     RGCSLSEISC DPLNSALKSN PSHLKHLDLS NNKLQDSGVK HLCGFLENPD CSLKTLRSGI
     MF
//