ID A0A3P8S1L7_AMPPE Unreviewed; 3643 AA.
AC A0A3P8S1L7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Crystallin beta-gamma domain containing 1a {ECO:0000313|Ensembl:ENSAPEP00000005429.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000005429.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000005429.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000005429.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the beta/gamma-crystallin family.
CC {ECO:0000256|ARBA:ARBA00009646}.
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DR Ensembl; ENSAPET00000005571.1; ENSAPEP00000005429.1; ENSAPEG00000003820.1.
DR GeneTree; ENSGT00940000155695; -.
DR OMA; DWDPHSE; -.
DR Proteomes; UP000265080; Chromosome 18.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.60.20.10; Crystallins; 6.
DR InterPro; IPR001064; Beta/gamma_crystallin.
DR InterPro; IPR011024; G_crystallin-like.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR11818:SF131; ABSENT IN MELANOMA 1 PROTEIN ISOFORM X1; 1.
DR PANTHER; PTHR11818; BETA/GAMMA CRYSTALLIN; 1.
DR Pfam; PF00030; Crystall; 6.
DR Pfam; PF00652; Ricin_B_lectin; 1.
DR SMART; SM00458; RICIN; 1.
DR SMART; SM00247; XTALbg; 6.
DR SUPFAM; SSF49695; gamma-Crystallin-like; 3.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50915; CRYSTALLIN_BETA_GAMMA; 9.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 2939..2978
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 2979..3011
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 3085..3127
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 3139..3192
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 3193..3235
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 3284..3326
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 3336..3373
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 3374..3418
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 3465..3506
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT REGION 1..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1068..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1276..1296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1301..1320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1333..1448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1481..1521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1533..2447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2462..2606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2623..2651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2719..2746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2758..2785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2885..2931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..575
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 679..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 727..741
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..787
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..830
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 831..855
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 895..920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 935..950
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..967
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 968..982
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1084..1100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1278..1296
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1335..1366
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1376..1395
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1424..1448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1489..1518
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1544..1560
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1561..1577
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1578..1592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1600..1619
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1626..1681
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1686..1745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1746..1771
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1772..1788
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1789..1805
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1806..1830
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1832..2011
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2029..2203
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2221..2290
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2291..2308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2315..2403
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2414..2429
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2462..2489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2525..2581
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2905..2925
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3643 AA; 398294 MW; B57CCEF98A134693 CRC64;
MSENDLESLE EKKGVFDRIS NFFRSGRKKS SSSRQPSDSS ASSPASPLSP RSSQSHEEDG
LKTPTPSRKD GELTGPHGAV PGSRLRAEHG DSLSQSSSPS ASSMASVVTK EAELPFADSD
SSGRSSVREV HVCTISTGCS DRNSGNVAAA ALHLPSTTEP AADSHSELGF TESVVEEVSK
RLQVHLEESI GKKTERSGED DMVTPTTLSS LQIPVSKTAE APKSPNLTSI SLASKTTVVK
IGGNGHSTAL TGITLGSHSS TSHIITTQQL EKSLDTERES TRARTSAQIS TVSGETTVTV
RSPSPEREPA PRGDSPIQLH KAIWVETHLG EEEEGEREGE KEKDIMNQGE EGLRADSPPV
LAIPVTVIPE DDSESPTAAD GPAAPSHILP TGGISPEAAT SLASTTREFQ ITSPQSAEPD
TSTDSKQSSL EEKHRPREIR VTRKTVTLPS KHKVFAQKVY ISPEPSVEED DLVGEECSGD
STSKIQNTTD ATPLASLQNK NNAEFKDANL ELSTTTDETT HSGTNTPEPV VKEKTDSEAS
DFDETSSASD MYKTKSQVVE SGVRGQGTSK TTLSKRGVKG AAESQHTAAS GTKTPSYAAG
GKAKNVITKA KGTTEGTKVE ISSDSPSQRE HSSEKAVSML PTLKDQSTSS PVSLTGSKSK
IPKRSTLDAE VKSPVTPDKT SLPDASGSTF TSKLQKQPRA KESLKSLTTT TKAIRKPSFE
EGKGGKSVSG NISSTKTTNK METKLNQDKS DKDCQSVESV SLVNGVENEN EERHVKTAHR
ESFNIKKQQQ NHLENNAPLA SKSSLPISSP ARKRNDDITQ TSGTTFRKAS SGHTDSDRPK
TVQKQSPEQQ EVTPDERSGS ETPPPLPESP KKAGSLPSVK GSRHPPKRST SRDDSDSPTS
CVSPPPAKQE KTVSSRLSKQ NDPVKQHRKS PVKHSSDTSG SVSKLPTRGQ RSFNRVKPRE
PQNSRDENSE DLSQNTSTEL TVKAPEKVEA DQVKDSDSFK FKSVSVEEEE HIIKLRDKQT
STGKIKLKEI ETKQLVEVIT NSTTEEISII QPSLKTDAII TENTQVNVAT GTDPGAGVSP
SSEVDKAIPS QSQVTDINKA ETDGLQHDVK KTKVEILPEN VSHVQSDKTV QGQKTLISAK
TSPEGKDKEI LEMTKPTSNM KLDLIQEKET NSAALAQDTI PAHEAVTDMS AKPVVGDGVH
CDTMTHSEQE GALPASISLT EITTVTSQEK EKEITRNSLP AKLASKDQDP EVKDLHSDTL
TVASVNAIQV NTEQQKELLK DQTTKEKDRL SPTLSTDLVK DLDVEQKSKD EVGRKPEEAL
DIQTETVTVC ELPKNVEHQS DKEALLLDRQ SEREEKDSKP NEKLGDAAME TSDSQNSCKK
ELKGKTIEGE AEKNITNSEK PCQLSPQEKH LQPETKEEPQ RVVTNALEKS SAKAEQASSA
LPETTPRVVD KNQQDVILLK ENAESGLKKI QGAEQQMKAS IVTEKQESKP LLTKQEEVRD
GNTHVDNKHA DDVKEKQTPE ITTLNTKMLD VKGDKEKKSL MNEVSNEAVE SEVSNQENKK
ALTARPKEPE TLKGPEKRTG SHISQTDTIK ELKAVSTEVL SGEGKKEDTE TEDLSLKSLR
TETETVTTNT EDDIHKDQKT RSGEDQDEDI TKPDKHPNDK LKEEQQTIRS KDQEKTTEKP
KMAPVLEQTS GSTATESSNK KAEFSNSSED SLVNETQTAN DKTVVSNQQV QVSQTITNQD
GSITKPEKSK SAESKCPKSD LNQESEAVRM EGSEESTASQ TQELKVKSSR TQSAEEAKEK
TEIKGRSMQT LVNEKTQSEI STQNDQKTSV VKEELVVIKE PRKTTDQSTD SKDPDANQKT
STVKEELVVI KEPGKSNDQS TDSKDPDAEK KTSIVKEELV ANKEPGKNTD QSTDSKDPDP
VHQKTSILKE ELVVIKEPGK TSDQSTDSKD TDAIQKTSIV KEELVVNKEQ GKTSDQSTDS
KDTDTIQKTS IVKEELVVNK EPGKTSDQST DSKDTDAIQM TSIVKEELVV NKEPGKTSDQ
STDGKDTDAI QKTSIVKEEL VVNKEQGKTS DQSTDSKDTD TIQKTSIVKE ELVVNKEQGK
TSDQSTDSKD TDTIQKTSIV KEELVVNKEP GKTSDQSTDG KDTDAIQKTS IVKEELVVNK
EQGKTSDQST DSKDTDAIQK TSIVKEELVV NKEPGKTSDQ STDSKDTDTI QMTSIVKEEL
VVNKEPGKTT DQSTDSKDPD ADHQKTSILK EELVVIKEPG KSTDQPTDGK DPDAEKKTSI
VKEELVANKE PQKNTDQSTD TQDPDANQKT SIVKEELVAN KEPGKGTDQS TDSKDTDANQ
KTLGVKEELV ANKEPGKSTD QSTDSKDPDD NRKTSGIKEE LVANKEPGKN TDQSTDSKDP
DANQEQKPNT VATEVPEKTD KEAKKTEILN VSTAERAASK PDVTPDQKNL IKEVVEVENK
IQKEVDQHPK AKQESELTLV KDVSSRKGSA EQKQKPTIVL NEIPISAAAQ NNDEDSKEKA
KTDESATVTF ATGDTLKQRL QTSREGQKPP KPTLDDSFSL SASKKSSAPS QSLQLKTESP
SSWLDVEHRP KRKKEHRRKL CPSASEDKTL ELDDFDNFIR SIKEGGIPFS RPPKRRIRRK
SPSPPFAMPA IKEDHFEKTF DPEKFQFGLG KNDKCFTDLS PAMVLKQKAA NRKGRTLEKR
SQDNLTTRHQ MTTVDEVEGK NGVKEGTNAV AGKEEGQNNG EEPGKMTSRL ERISILSSLM
NSPHSRRKTT EETTIASNSK HSSDQQQNLL TLGKLGLTNS PVPDIKADNG DVKDIDQGSF
TGGGIGTVSE SALSPSSAPP PPLFSEVKLP DHLEKYLKKN KRESEPSQVS TQMTETDLIS
KERTAMDQAS VSDGPNVDSS LKGPAGLPSI TNYSQKTSRN GLSTKTKIPA ERGFHKRPGK
IVIHEHAQFG GEVFQLHRDV EDATAMKLSP VISVRVIRGC WLLYEKPGFQ GRIIALEEGP
TDQIVNMWAE EGTPETLDRM GQPVPTAPMV IGSVRLAVRD YSMPRIDLFQ EVNGLGRVSS
YCDVAVEVSS YGIPQTTGSI KVHSGVWLVY TDPGFNGFVG VLDVGEYPCP ETWGFPEPFV
GSLRPLRMGA IRVEHPNEVK ALVFEKPNFE GECMEVDSDV YNLQEQEDKE EADKADVNKK
GLSAVGSIKI LGGLWVGYQE ADFEGQQYVL EEGEYPHCSD WGGSQHGLQS LRPVVTDFLS
PHLKLFSEPN FNEMGLKVDL LGPVISMEDI GHGIKTQSVS VTSGVWVAFE KPGFSGELYV
LEKGLYAHPE DWGAPHFKIS SIQPVFHDML VGTTKFKVQL YSEPDFQGRL VALEDSAAAL
DEDFTPRSCK VLAGSWVAYD GVRFTGNMYV LEEGEYPNTE SMGFLSSDSH IRSVQTAGHE
FSLPSIILFT KVGCRGRRMV LTDGAVNLLQ AGGDAQTRSL VVEGGMWVLY EGSNYRGRQL
LLQPCQVGDL CQYSSWQRIG SLRPLLQKQM YFRLRNRETG CVMSLTGTLE DIKLMRVQAV
EETRGLEQVW LYRDGQLSCK LVEDCCLATG GSMVMAGCRL CVSPERGKDA QLWNITPDGL
VRSHLKPELV LEVKGGHQYD KNQVILNTFD DRKVTQRWTL EIL
//
