ID A0A3P8S1V2_AMPPE Unreviewed; 505 AA.
AC A0A3P8S1V2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Protein tweety homolog {ECO:0000256|RuleBase:RU361114};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000006843.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000006843.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000006843.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Probable chloride channel. {ECO:0000256|RuleBase:RU361114}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the tweety family.
CC {ECO:0000256|ARBA:ARBA00009849, ECO:0000256|RuleBase:RU361114}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU361114}.
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DR AlphaFoldDB; A0A3P8S1V2; -.
DR Ensembl; ENSAPET00000007020.1; ENSAPEP00000006843.1; ENSAPEG00000004869.1.
DR GeneTree; ENSGT00950000183060; -.
DR OMA; HYYLFCR; -.
DR Proteomes; UP000265080; Chromosome 14.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-UniRule.
DR CDD; cd07912; Tweety_N; 1.
DR InterPro; IPR006990; Tweety.
DR PANTHER; PTHR12424:SF17; PROTEIN TWEETY HOMOLOG 2-LIKE; 1.
DR PANTHER; PTHR12424; TWEETY-RELATED; 1.
DR Pfam; PF04906; Tweety; 2.
PE 3: Inferred from homology;
KW Chloride {ECO:0000256|RuleBase:RU361114};
KW Chloride channel {ECO:0000256|RuleBase:RU361114};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|RuleBase:RU361114};
KW Ion transport {ECO:0000256|RuleBase:RU361114};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361114};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361114};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361114};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361114}.
FT TRANSMEM 45..73
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 85..109
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 213..235
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 362..387
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
SQ SEQUENCE 505 AA; 56525 MW; 68ED78DABF7AFED9 CRC64;
MATARLDYVA PWWTYWLHNF PHFNFLFQSV DSTFKPGEAS YQQSLIFLAC VGAVGLGLSL
LVLAIFLVCL CCCRKDVDED TKRPNTCCVT LVAVVTGLII CSAVGVGFYG NSETNDGVYQ
LTYSLYNANH TLGGINNLIS GSQGSVGTGL KEHLERLDEI FATRADYLQA LRFLQLMVNN
VIRELTALPD ISKTNVDLAA IADQTAFIEY YRWLSYLLLL ILDLVICLAM CLGMAKHSQC
LLITDFCVSP DKFIVNQTKD FLSTDVAHYY LFCRPNLPNP FQQSLTICQR SLTTMQIQIQ
GLLQFSVPVF PTAERDLLGI QRLLNFTEFN LHQLTAFLDC RGLHKDYLEA LMGVCYDGVE
GLLYLSLFSL LAACALSTML CAIFRVWTLM GSRLYDDIDE EDPFNPQAQR ISYNPRRSNT
HSFCSYTSSL GSQASLHPPP QSASNIMPPP EYMNQSMLFG GTPRYENVPL IGRGSPPPSY
SPSMRTTYLS MTDAQIRHFG TDFQV
//
