ID A0A3P8S4C5_AMPPE Unreviewed; 2035 AA.
AC A0A3P8S4C5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 10-FEB-2021, entry version 9.
DE SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSAPEP00000007106};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000007106, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000007106, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000007106}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (DEC-2018) to UniProtKB.
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DR Ensembl; ENSAPET00000007292; ENSAPEP00000007106; ENSAPEG00000004920.
DR GeneTree; ENSGT00730000111187; -.
DR Proteomes; UP000265080; Chromosome 1.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 4.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT DOMAIN 1..283
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1354..1482
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 1578..1637
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 1902..1946
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 116..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 420..491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1843..1876
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1889..1913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1992..2035
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 20..82
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 151..178
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 256..346
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 693..734
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 749..776
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 790..824
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 828..848
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 895..922
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 944..971
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 979..1027
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1050..1186
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1194..1214
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1222..1325
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1358..1392
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1421..1441
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1449..1490
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1554..1637
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1822..1842
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 117..143
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..434
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..462
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..491
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..560
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1843..1868
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1995..2013
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2018..2035
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2035 AA; 233672 MW; FAEB9B8CA02FF756 CRC64;
MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKERTQKQFQ LDSLEAALQK QKQKVDSERS
EISSLKRENQ SLVESCDSLE KARQRVTHDL GEEINIFRCF KQHRLKCIGY KNELDRSQPA
GSASLSSSSA DLQPYTTPQK SFATPAPVPA YRQQDNRLEE LQEKYNQEVE ERKKLETDLK
VLGFTCLFCF SSGSSIFPWQ QQDQAHSRQS QDAMETPLKR RGTSLWDAHE ETPIKPSQRM
SCSVAVQSPS GSSKQMEQLK TLNQELRGRV SELERNLSNQ EKEIRNQASK LQELQTQLNQ
ACKDLTERDR DLAKTSHELS QATDRHQQVE AKCSSVEQKL KQVTEEMSCQ RHNAESCKRA
LEQKLKDQER DSQKELAQLQ NSHQALDQQL NQTRTKLTQE IQQSKKDYNI LQADMEKVKG
QMEKEMEEQK QRLLRSEQSL QANQTKEQDL RKKMEELQKE KNSMTVQLDQ SNRRLSQLEE
EKKSSEQSFK RTQGLLDDLK AKSEGQAEEL KKLQSRLEQQ TQASAREQEH LKKTLSDAET
KNDRSQNELQ KQKQEAERLS NRLTVLDKES QELKSNLTAS QNECTKLKQE HQALVEWKTE
KETLINETEA MQKELSDKIN NLESSVSSLN ETNGELQKKL MCAEREKASL SSHIDSLKGE
VLNKSTELEE KEHQYKELQS QFSEAGQKHT KDLENVGMQV AQLESQVKDL ELQLQKEITR
AELAERTNTE LQEEHQAACD LVRSKDQLID LGQTEISQLR ESLAQATAQQ EEQNARWDLL
TQQFCFQILQ HSHTEKINTL LDQISSLEEK MAASEDAAEK LLVLQNDLDV VNQSYADLKD
SLEALEKSHS STIEIKSNLE NSLSEKSELI CALEKEIKDL TEKMSKESES HTLEIENFVN
KEKNLKEQLE ATKKSINAAK AESSSRREEI KTMKTTLSAA SRGLEQRDNT IKSLKQKLNE
AEAEHAKTSD LLKEKVVAMN KIKVQLEMLQ MDLEDNETAM NSFDGQVEEL KGTIELLEAQ
LVQSQNSVLE TKYVTAKEEL LERSCEISRL EEDAVKRNQL EETVASLESK LSQMTEENAK
LETSIRQMVQ DKDNNINQLL QQKNHLETSL KQLMHDKEQI EAEIIQINTE KKQLETSLEE
LSEQNKQLQT NIQQLTEEKQ QTQARIEEMT AEKHEAELAL SQVIEEKAQF DVTLHQIKEE
KTELQSNLSA LISEKCDLVT NLNQAVEEKL QLESNYNQLS EENIKLQSHV NEVTEEKLKL
QENIVRHQDE VTSLREENES IQSSLLSSEQ ERQRLKEQLE MRDELTQLSE EKETLTLQLQ
TAKCQLTDVM EMLEGLEMAK DFKLQLYLFI CFMVRSEKAN LEQHILGMES ELETMQVEKT
RLTDEMETQK KTSSGMEQQI ETLMTETTQL RSELVSCSEE RDELSQSLGQ WKEKVHTLEK
TNCDTRHLIS ILEDDIRAGR KEYEALQSNM EKLKTERQQL MEQVKLLEQA VSQQCGEREE
LIGHLNQIKE DHTSANENTE SMMGKIQALE GEVCRLSQSL ESSLLEKGEI ASRLNSTQEE
VQQMRTGIEK LQVRIESDER KKKKMGELLK AAQRKSDSLQ DRIDALEREK EDVEQSLEDA
VLQAETAKAE LEEERTKVPS CYSNWLSLYL CSKNRFVGAQ IHACIALKCL SRQNVKHSVY
IILKSKMLNN IWKKGSGNER ILRFDLCMMT LGKLLMIKVR LICLLKHCFV LFFQVSELTS
CAARLSKERD SALSKINLWM KTCKQLEQEK QMMLISSGVL KRSKFNIRFP SSQEKNKELK
ELMKSKEADD SMDKYCSLMV KVHKLEETND ALKTRLEQVT ATQRADAANS LASSTDSRRS
PQGSSSGKRG HRDISDKDSA QEALHNLTKK IKANAMTTPK PRAEQDDEEF RPEGLPELVQ
KGFADIPLGE ASPFIIRRTT AKRCSPRLAA RQALHTSAPD GKVSSTLPSF FYTVWYSACA
TCTSSQLQNN TLKRHSPSSE EKPVHRSLSL LKTPEQKEKQ LVGQQTQQGD NCHVQ
//
