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Database: UniProt
Entry: A0A3P8S4C5_AMPPE
LinkDB: A0A3P8S4C5_AMPPE
Original site: A0A3P8S4C5_AMPPE 
ID   A0A3P8S4C5_AMPPE        Unreviewed;      2035 AA.
AC   A0A3P8S4C5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   10-FEB-2021, entry version 9.
DE   SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSAPEP00000007106};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000007106, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000007106, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000007106}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (DEC-2018) to UniProtKB.
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DR   Ensembl; ENSAPET00000007292; ENSAPEP00000007106; ENSAPEG00000004920.
DR   GeneTree; ENSGT00730000111187; -.
DR   Proteomes; UP000265080; Chromosome 1.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 4.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT   DOMAIN          1..283
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1354..1482
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          1578..1637
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          1902..1946
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          116..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          201..222
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          420..491
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          506..560
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1843..1876
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1889..1913
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1992..2035
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          20..82
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          151..178
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          256..346
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          693..734
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          749..776
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          790..824
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          828..848
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          895..922
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          944..971
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          979..1027
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1050..1186
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1194..1214
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1222..1325
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1358..1392
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1421..1441
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1449..1490
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1554..1637
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1822..1842
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        117..143
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        420..434
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        446..462
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        474..491
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        523..560
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1843..1868
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1995..2013
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2018..2035
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2035 AA;  233672 MW;  FAEB9B8CA02FF756 CRC64;
     MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKERTQKQFQ LDSLEAALQK QKQKVDSERS
     EISSLKRENQ SLVESCDSLE KARQRVTHDL GEEINIFRCF KQHRLKCIGY KNELDRSQPA
     GSASLSSSSA DLQPYTTPQK SFATPAPVPA YRQQDNRLEE LQEKYNQEVE ERKKLETDLK
     VLGFTCLFCF SSGSSIFPWQ QQDQAHSRQS QDAMETPLKR RGTSLWDAHE ETPIKPSQRM
     SCSVAVQSPS GSSKQMEQLK TLNQELRGRV SELERNLSNQ EKEIRNQASK LQELQTQLNQ
     ACKDLTERDR DLAKTSHELS QATDRHQQVE AKCSSVEQKL KQVTEEMSCQ RHNAESCKRA
     LEQKLKDQER DSQKELAQLQ NSHQALDQQL NQTRTKLTQE IQQSKKDYNI LQADMEKVKG
     QMEKEMEEQK QRLLRSEQSL QANQTKEQDL RKKMEELQKE KNSMTVQLDQ SNRRLSQLEE
     EKKSSEQSFK RTQGLLDDLK AKSEGQAEEL KKLQSRLEQQ TQASAREQEH LKKTLSDAET
     KNDRSQNELQ KQKQEAERLS NRLTVLDKES QELKSNLTAS QNECTKLKQE HQALVEWKTE
     KETLINETEA MQKELSDKIN NLESSVSSLN ETNGELQKKL MCAEREKASL SSHIDSLKGE
     VLNKSTELEE KEHQYKELQS QFSEAGQKHT KDLENVGMQV AQLESQVKDL ELQLQKEITR
     AELAERTNTE LQEEHQAACD LVRSKDQLID LGQTEISQLR ESLAQATAQQ EEQNARWDLL
     TQQFCFQILQ HSHTEKINTL LDQISSLEEK MAASEDAAEK LLVLQNDLDV VNQSYADLKD
     SLEALEKSHS STIEIKSNLE NSLSEKSELI CALEKEIKDL TEKMSKESES HTLEIENFVN
     KEKNLKEQLE ATKKSINAAK AESSSRREEI KTMKTTLSAA SRGLEQRDNT IKSLKQKLNE
     AEAEHAKTSD LLKEKVVAMN KIKVQLEMLQ MDLEDNETAM NSFDGQVEEL KGTIELLEAQ
     LVQSQNSVLE TKYVTAKEEL LERSCEISRL EEDAVKRNQL EETVASLESK LSQMTEENAK
     LETSIRQMVQ DKDNNINQLL QQKNHLETSL KQLMHDKEQI EAEIIQINTE KKQLETSLEE
     LSEQNKQLQT NIQQLTEEKQ QTQARIEEMT AEKHEAELAL SQVIEEKAQF DVTLHQIKEE
     KTELQSNLSA LISEKCDLVT NLNQAVEEKL QLESNYNQLS EENIKLQSHV NEVTEEKLKL
     QENIVRHQDE VTSLREENES IQSSLLSSEQ ERQRLKEQLE MRDELTQLSE EKETLTLQLQ
     TAKCQLTDVM EMLEGLEMAK DFKLQLYLFI CFMVRSEKAN LEQHILGMES ELETMQVEKT
     RLTDEMETQK KTSSGMEQQI ETLMTETTQL RSELVSCSEE RDELSQSLGQ WKEKVHTLEK
     TNCDTRHLIS ILEDDIRAGR KEYEALQSNM EKLKTERQQL MEQVKLLEQA VSQQCGEREE
     LIGHLNQIKE DHTSANENTE SMMGKIQALE GEVCRLSQSL ESSLLEKGEI ASRLNSTQEE
     VQQMRTGIEK LQVRIESDER KKKKMGELLK AAQRKSDSLQ DRIDALEREK EDVEQSLEDA
     VLQAETAKAE LEEERTKVPS CYSNWLSLYL CSKNRFVGAQ IHACIALKCL SRQNVKHSVY
     IILKSKMLNN IWKKGSGNER ILRFDLCMMT LGKLLMIKVR LICLLKHCFV LFFQVSELTS
     CAARLSKERD SALSKINLWM KTCKQLEQEK QMMLISSGVL KRSKFNIRFP SSQEKNKELK
     ELMKSKEADD SMDKYCSLMV KVHKLEETND ALKTRLEQVT ATQRADAANS LASSTDSRRS
     PQGSSSGKRG HRDISDKDSA QEALHNLTKK IKANAMTTPK PRAEQDDEEF RPEGLPELVQ
     KGFADIPLGE ASPFIIRRTT AKRCSPRLAA RQALHTSAPD GKVSSTLPSF FYTVWYSACA
     TCTSSQLQNN TLKRHSPSSE EKPVHRSLSL LKTPEQKEKQ LVGQQTQQGD NCHVQ
//
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