ID   A0A3P8S4E2_AMPPE        Unreviewed;       226 AA.
AC   A0A3P8S4E2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Claudin 34 {ECO:0008006|Google:ProtNLM};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000006875.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000006875.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000006875.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC       {ECO:0000256|ARBA:ARBA00004435}.
CC   -!- SIMILARITY: Belongs to the claudin family.
CC       {ECO:0000256|ARBA:ARBA00008295}.
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DR   AlphaFoldDB; A0A3P8S4E2; -.
DR   STRING; 161767.ENSAPEP00000006875; -.
DR   Ensembl; ENSAPET00000007051.1; ENSAPEP00000006875.1; ENSAPEG00000004921.1.
DR   GeneTree; ENSGT00390000005717; -.
DR   OMA; LGLIQWR; -.
DR   Proteomes; UP000265080; Chromosome 24.
DR   GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR006187; Claudin.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   PANTHER; PTHR12002; CLAUDIN; 1.
DR   PANTHER; PTHR12002:SF4; CLAUDIN-34; 1.
DR   Pfam; PF13903; Claudin_2; 1.
PE   3: Inferred from homology;
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW   Tight junction {ECO:0000256|ARBA:ARBA00022427};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        87..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        123..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        174..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   226 AA;  24200 MW;  F3C576DECFC12216 CRC64;
     LPLKEEGNSL CALWLACVGW TLTAVALGLV QWRVWLVSHS EAISSGVAWV GVWRTCFNSR
     TVASPGFTVM HCSRIGLTEE FTPPEIAAAQ VLMMLSLLVG LCGNAGGVYA MRNACFGLDE
     NPPIRLCFVA TGALCLLAAG MSSVPVIWNL SSVATNRTIR FPPEFKMPAA PDSQHVGCGV
     VVGMVGTVLM VMSGVIFCTY RSPVSRLLHR SPQGTDNPAF VLHEHL
//