ID A0A3P8S8I0_AMPPE Unreviewed; 761 AA.
AC A0A3P8S8I0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb {ECO:0000313|Ensembl:ENSAPEP00000007944.1};
GN Name=SEMA6B {ECO:0000313|Ensembl:ENSAPEP00000007944.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000007944.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000007944.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000007944.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR AlphaFoldDB; A0A3P8S8I0; -.
DR Ensembl; ENSAPET00000008177.1; ENSAPEP00000007944.1; ENSAPEG00000005674.1.
DR GeneTree; ENSGT00940000159170; -.
DR Proteomes; UP000265080; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0022008; P:neurogenesis; IEA:UniProt.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF10; SEMAPHORIN-6B; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT DOMAIN 1..452
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 559..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 761 AA; 84999 MW; AD6EAF23BB9FDEF9 CRC64;
IRPPDVVIGI TYYILRDDKK RNKKKKGCSR IRKMCKSFYD LNLFGDSVTP NMRILIDECR
NFMKVLLSRQ GGLFLCGTNA FNPLCANYTG DNLEMVGDTV SGMARCPYDP KHANVALFAE
GNLFTATVTD FLAIDAVIYR SLGDSPALRT VKHDSKWFRE PYFVSAVEWG PHIYFFFREI
AMEFNYLEKV VVSRVARVCK RDQGGSQRVL EKQWTSFLKA RLNCSVPGDS HFYFNLLHST
SPIIRMHGRD IILGVFSTPA NSIPGSAVCA FDMEQLAAVF DGRFKEQKSP ESIWTPVPDE
VIPKPRPGGC AVQGSRFNSS NSFPDEMLNF VKTHPLMDEA VPSLGQRPWI VRTMVRYQLN
KMVVDTEAGP YRNRTVLFLG SSRGTILKFL IMPNPDNTVT NSNIFLEELE GFNPDKCAED
SPQARQLLSL TLDRASHTLL LAFPSCVVRV PVARCQLYSR CMKNCIASRD PYCGWTRGST
CSFLRPGTRL PFEQDVEQGN VAHLGDCDGM LLQESFIEEP DGLVSVNLLV VSAVSAFATG
AILSGLTVCW IMSHRHRHSR SSGANGARRK RDKEQSMLGQ GHSGSVMSVT RTSGGERRRS
QADNPFVTPN GWPKGEMDPG LLPTPEQTPL QQKRAMRLPD PDWDQSQTFL TAVGTPCPNN
SVIYLSSKFL NSAGEYIYPA TPQDSPDRRR VVSAPTPHMD YGEPRWSHEA LNYNSNNGAP
YHPQRQGLIR PDMHGPRGLG ELADFSHLLG KNMGERTPSG Q
//
