ID A0A3P8SAD3_AMPPE Unreviewed; 1135 AA.
AC A0A3P8SAD3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=AF4/FMR2 family, member 3 {ECO:0000313|Ensembl:ENSAPEP00000009241.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000009241.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000009241.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000009241.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AF4 family. {ECO:0000256|ARBA:ARBA00007354}.
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DR AlphaFoldDB; A0A3P8SAD3; -.
DR STRING; 161767.ENSAPEP00000009241; -.
DR Ensembl; ENSAPET00000009494.1; ENSAPEP00000009241.1; ENSAPEG00000006641.1.
DR GeneTree; ENSGT00950000182974; -.
DR OMA; PKIEAEC; -.
DR Proteomes; UP000265080; Chromosome 12.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR InterPro; IPR007797; AF4/FMR2.
DR InterPro; IPR043640; AF4/FMR2_CHD.
DR PANTHER; PTHR10528; AF4/FMR2 FAMILY MEMBER; 1.
DR PANTHER; PTHR10528:SF16; AF4_FMR2 FAMILY MEMBER 3; 1.
DR Pfam; PF05110; AF-4; 1.
DR Pfam; PF18876; AFF4_CHD; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT DOMAIN 882..1134
FT /note="AF4/FMR2 C-terminal homology"
FT /evidence="ECO:0000259|Pfam:PF18876"
FT REGION 1..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 706..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 807..887
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1028..1053
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..249
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..337
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..510
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..588
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..616
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 708..730
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..769
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 819..836
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 837..859
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1036..1053
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1135 AA; 126474 MW; B10BD16E1368C553 CRC64;
MGRHPHVAPH KSMLADDLKL SSDDEDNQRP IHESVSWDRH SLSAQRAHTN GRRVRYSSSN
SSGSDSTVES GSSSLHSRSP SRSPEVHPEP ASPVDTHPSC HNEETDHPSA AQWQLDKWLK
KSQKKSARSE QDPSQSIPGH LLSPHTQRAP SPALSWDSNQ EYSPSQSPIP SPQFSYSHNH
GSLPSPGYSY CPSPSPFPST CPSPSPSPRH SPIPSPVPSV CPSPCGSPGA SRSPSPIPRD
PPRSPSPSVP APSRVCHYPE VQSHHPGLTT NPHRTKIRPW IAPNADTKSK PTSNTHLQHR
PKHRPPPDRD QNQNQSKSKI SVVLSSNQSQ SCKSRLKPIF HSSPKELAEV PQAKNTSHHQ
SSRSNPRSRP PFHPSSQRSP TRAKRLVPSS CEANTGHSSH SQSTSKAAHN SSTGLNRRSI
SSLKHRSKSL EATAPTSTHV NQAKSSQKKP EAKEQEVEHR RDHLTHVERR KHERKEDRHR
EKLEGKPERK EDKRLAEEQL LRRPWIHSSA EEEEEEEEED DGVIERQRRR EEAARAENRR
KREQQHRHEW PKQRGPSSSE RHRLQDDSHH QGRTKKGPRS EEDRDFSPPL PSRSPSPHRP
SSSASSSSNS DSESECQAPV AKAPADSTSH KRLTKKGQDP GGPDANRPRV VQPRGASSGT
PSKEQQSEGK QKLYTLVPFG RSEKAPPSSQ RGLRNLVVHI DLCLLKRVPD STTNSPVKNP
SSSSSSASNK DKQREAMKHL FVPETPTKDN KRKRKLENGV SHRESKRSLP YANDLSGPTE
SSSLTAENLV TGTTHNGYLE EYLDSKRPLS PLSPLSPLPQ SPESTKSTSK TKAPEQQNTP
KNKDKNRDSA IKPKMEVECV KVSKQPQPPS ETWGPAGHRG TVPNHETPHH AEYYLHEAKR
MKHRADAMVD KLGKAVNYVD AALSFMECGK AMEEGPLEAK SPYTMYSETV ELIRYAMRLK
SHSGPGARQE DKQLAVLCFR CLALLYWQMF RLKKDHALKY SKVLLDYFKS SPKVPTTPPC
WTDYRKGAGG PPSSLSPNAK HISRGSHGGS SSSASLISIP QRIHQMAANH LNITNSVLYS
YEYWEVADNL AKENKEFFNY LNTLSGPLTL HSSIAHAVQY TRQALQWIRI SAKLN
//
