ID   A0A3P8SFQ6_AMPPE        Unreviewed;       316 AA.
AC   A0A3P8SFQ6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Transducer of ERBB2, 1a {ECO:0000313|Ensembl:ENSAPEP00000011448.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000011448.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000011448.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000011448.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the BTG family. {ECO:0000256|ARBA:ARBA00007989}.
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DR   AlphaFoldDB; A0A3P8SFQ6; -.
DR   STRING; 161767.ENSAPEP00000011448; -.
DR   Ensembl; ENSAPET00000011756.1; ENSAPEP00000011448.1; ENSAPEG00000008187.1.
DR   GeneTree; ENSGT00940000154208; -.
DR   OMA; YRMGERG; -.
DR   Proteomes; UP000265080; Chromosome 14.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   Gene3D; 3.90.640.90; Anti-proliferative protein, N-terminal domain; 1.
DR   InterPro; IPR002087; Anti_prolifrtn.
DR   InterPro; IPR036054; BTG-like_sf.
DR   InterPro; IPR015676; Tob1/2.
DR   PANTHER; PTHR17537; TRANSDUCER OF ERBB2 TOB; 1.
DR   PANTHER; PTHR17537:SF7; TRANSDUCER OF ERBB2, 1A; 1.
DR   Pfam; PF07742; BTG; 1.
DR   PRINTS; PR00310; ANTIPRLFBTG1.
DR   SMART; SM00099; btg1; 1.
DR   SUPFAM; SSF160696; BTG domain-like; 1.
DR   PROSITE; PS00960; BTG_1; 1.
DR   PROSITE; PS01203; BTG_2; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT   DOMAIN          40..60
FT                   /note="Anti-proliferative protein"
FT                   /evidence="ECO:0000259|PROSITE:PS00960"
FT   DOMAIN          86..105
FT                   /note="Anti-proliferative protein"
FT                   /evidence="ECO:0000259|PROSITE:PS01203"
FT   REGION          150..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..169
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   316 AA;  34310 MW;  0425357CDC87EE40 CRC64;
     MQLEIQVALN FIISYLYNKL PRRRVNIFGE ELERQLKQKY EGHWYPDKPY KGSGFRCIHV
     GEKVDPVVEK AAKESGLDIE DVRNNLPQDL SVWIDPFEVS YQIGEKGPVK VLYVDDTNES
     GATNGGLDLD KEIKNSFNPD AQVFMPINEP VNGASPGSSS PSPPFGHSAA VSPTFMPRST
     QPLTFTTATF AATKFGSTKM KSSGRNNNGG GGGGAISTSM HSLYGLGLGA QQHQKPSALS
     PNAKEFVFPS LQGQGSQSAL FPGDSSLSLS PLQYSNAFDM FAAYGGLNDK SLMDGLNFSL
     SNMQYSNQQF QPVMAN
//