ID   A0A3P8SGF1_AMPPE        Unreviewed;       523 AA.
AC   A0A3P8SGF1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Doublesex and mab-3 related transcription factor 2a {ECO:0000313|Ensembl:ENSAPEP00000010889.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000010889.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000010889.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000010889.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00070}.
CC   -!- SIMILARITY: Belongs to the DMRT family.
CC       {ECO:0000256|ARBA:ARBA00006834}.
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DR   AlphaFoldDB; A0A3P8SGF1; -.
DR   STRING; 161767.ENSAPEP00000010889; -.
DR   Ensembl; ENSAPET00000011188.1; ENSAPEP00000010889.1; ENSAPEG00000007763.1.
DR   GeneTree; ENSGT00940000156282; -.
DR   OMA; WDLKGTR; -.
DR   Proteomes; UP000265080; Chromosome 5.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
DR   Gene3D; 4.10.1040.10; DM DNA-binding domain; 1.
DR   InterPro; IPR001275; DM_DNA-bd.
DR   InterPro; IPR036407; DM_DNA-bd_sf.
DR   InterPro; IPR026607; DMRT.
DR   PANTHER; PTHR12322; DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT; 1.
DR   PANTHER; PTHR12322:SF53; DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 2; 1.
DR   Pfam; PF00751; DM; 1.
DR   SMART; SM00301; DM; 1.
DR   SUPFAM; SSF82927; Cysteine-rich DNA binding domain, (DM domain); 1.
DR   PROSITE; PS40000; DM_1; 1.
DR   PROSITE; PS50809; DM_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00070};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU00070};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00070}; Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00070}.
FT   DOMAIN          73..120
FT                   /note="DM"
FT                   /evidence="ECO:0000259|PROSITE:PS50809"
FT   DNA_BIND        73..120
FT                   /note="DM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00070"
FT   REGION          16..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          361..421
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        395..421
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   523 AA;  57290 MW;  AC321CD01523E0F3 CRC64;
     MSDSTGCEFE IDVESLETES DDLADSCSRP GSAPLGPAAS EDDGDGTKGD DRPGPSGGLC
     SGDQRKLSRT PKCARCRNHG VVSCLKGHKR FCRWRDCQCA NCLLVVERQR VMAAQVALRR
     QQATEDKKGL SGKQIPAERR TIYQRHIRPS SMLAKSILEG YRPVPSDPFL ATNPSLPPPL
     SDRMRKRRAF ADKELETIML EREYKERELM ENSQTAPGSL LFPNSMVHHA AEYNSYKTAY
     SPAAQVEPQP KELCGFLGPN CLDLGMQYPS SSANVELISS NVSVATTYRH YPLQPSRGGF
     MMWPRGAANL GDALLYQQCL FNATAVQNMK PGAVWEPKVM PAESQPPDQE VALAAKLEGS
     RAAMLQDSSD PQRADPKPPG ATHAGPRECS AFSPPKRSFG QSFPSNPHSQ NSSQVQNKPS
     KDKLSMKLNS FHSLIQHSLS EKAGGGSGPE LRAPYCKELL EEAARKFREG SAKDIQAVKI
     TDRYAKDFLS KPVGTKMASS ESLSFSVEAI LKRPTPAMSR AFH
//