ID   A0A3P8SI17_AMPPE        Unreviewed;       459 AA.
AC   A0A3P8SI17;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Formin-like 2b {ECO:0000313|Ensembl:ENSAPEP00000011791.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000011791.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000011791.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000011791.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the formin homology family.
CC       {ECO:0000256|ARBA:ARBA00023449}.
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DR   AlphaFoldDB; A0A3P8SI17; -.
DR   Ensembl; ENSAPET00000012102.1; ENSAPEP00000011791.1; ENSAPEG00000008331.1.
DR   GeneTree; ENSGT00940000155515; -.
DR   Proteomes; UP000265080; Chromosome 24.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   InterPro; IPR014767; DAD_dom.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR043592; FMNL_animal.
DR   PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR   PANTHER; PTHR45857:SF1; FORMIN-LIKE PROTEIN 2 ISOFORM X1; 1.
DR   Pfam; PF02181; FH2; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51231; DAD; 1.
DR   PROSITE; PS51444; FH2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT   DOMAIN          1..381
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   DOMAIN          413..447
FT                   /note="DAD"
FT                   /evidence="ECO:0000259|PROSITE:PS51231"
FT   REGION          378..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        385..420
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   459 AA;  53116 MW;  316C48A127BBCF82 CRC64;
     MPVLNWVALK PSQINGTVFN DIDDESILQD LDVEEFEEMF KTKAQGPAVD LTLSRQKLPQ
     KAPSKVSLLE ANRAKNLAIT LRKAGQGSEV ICRAIHTFDL RTVRVDFVEC LMRFLPTDSE
     VKLLRQYERD RKPLEALSDE DRFMLQFSRI ERLSQRMNIM TFMGNFTDNV QMLTPQLHAI
     IAASVSIKSS QKLKKILEII LALGNYMNSS KRGAVYGFKL QSLDLLLETK STDRKQTLLH
     YIANVVREKY SSVSLFYNEL HYVDKAAAVS LENVLCDVKE LQRGMELTWR EFSVSHNATL
     KDFISRNESR LSKLQEDARI AQDAFEDAVK FFGESSKTMP PSVFFPIFVR FIKAYRLAEE
     ENEQRRRQEQ MLLEKLEQEE QLQEEEETKS PSHRGKRQQQ ELITELRRRQ GKDSRHVYEG
     KDGAIEDIIT ALKTVPFTAR SAKRSSRFFC DPAHSEEHY
//