ID A0A3P8SIW4_AMPPE Unreviewed; 707 AA.
AC A0A3P8SIW4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Sema domain-containing protein {ECO:0000259|PROSITE:PS51004};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000011874.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000011874.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000011874.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR AlphaFoldDB; A0A3P8SIW4; -.
DR Ensembl; ENSAPET00000012186.1; ENSAPEP00000011874.1; ENSAPEG00000008377.1.
DR GeneTree; ENSGT00940000154870; -.
DR Proteomes; UP000265080; Chromosome 17.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0022008; P:neurogenesis; IEA:UniProt.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF145; SEMAPHORIN-4A ISOFORM X1-RELATED; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 615..637
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..449
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 534..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 707 AA; 79207 MW; 36358A948EAFA447 CRC64;
SPGRNLIRFS NHNVRNTTTL LLSQDGDMLY VGARDSVLAL DVRHDDIILK SKLDWSPPDK
DLEQCSMKGK KMDCPNFIRV LQFLNTTHLY ACGTFAFSPR CIYIQDSETL TMSLKPDEGR
GRCPYDPYQR NTAIIVGELY TGTVADYRGN RPVISRYLSE GSRVDLKLDD TLGWLEPTFI
RSTFLPDEGK IYFFFSEVGR EYDFIDKFIV SRISQICTSD VGGQRTLQRR WTTFAKAQLL
CQADNELPYN VIQDIDTLLP ADGAPEDDTL FYGIFTSSVN SGRSAVCSFR LTDIKSVFTG
NYKVLNRDTL QWRAWVQEKV ANPGECGLHN ASDNVLRFVK ENFLADESVR PVGRSLTMVS
AEHNYTHLAV QRVQAANSRH YTVLFLLTLQ GVIYVGTSEG VVKVPTANCS FYWTCAQCVL
ARDPFCHWDP VSRTELVSVS LNEVIRIQCP AASQLSQQVW ERPNSRLSSD LYLFLEDGSL
SFVATPATLG HYLCLSFENG YQQTMAIYHV KQKSSPMTQS PTRFPRPQTY PIPTTQAVSR
HGPELHTSVG TSPKRTESTN EEIRPTLSIR NTQVTRGQFG RNLILWTEKS GQKETEFKGG
EPLLAAKGPC YLRELVVVSV LLVICLSLLI TMVLYALRQR CRSRTAPQAG TANRDSDRRT
PVEQEALSGN NILSKHNGQA LHSGHVSGLF CNGTLTGPNG HLPNTPS
//
