ID A0A3P8SLJ7_AMPPE Unreviewed; 620 AA.
AC A0A3P8SLJ7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|Ensembl:ENSAPEP00000012944.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000012944.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000012944.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000012944.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; A0A3P8SLJ7; -.
DR STRING; 161767.ENSAPEP00000012944; -.
DR Ensembl; ENSAPET00000013291.1; ENSAPEP00000012944.1; ENSAPEG00000009187.1.
DR GeneTree; ENSGT00940000153511; -.
DR OMA; TFANERI; -.
DR Proteomes; UP000265080; Chromosome 17.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21067; NURR_hnRNPR; 1.
DR CDD; cd12250; RRM2_hnRNPR_like; 1.
DR CDD; cd12494; RRM3_hnRNPR; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR041337; hnRNP_Q_AcD.
DR InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01648; hnRNP-R-Q; 1.
DR PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR PANTHER; PTHR21245:SF5; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R; 1.
DR Pfam; PF18360; hnRNP_Q_AcD; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 165..244
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 246..328
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 341..411
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..606
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 620 AA; 69219 MW; 3B1B37D9591B8DBE CRC64;
MAAAEVNGSS APAKEEEEPM DVTTTHTENY QTLIDAGLPQ KVAESLDNIF QTGLVAYVDL
DERAIDALRE FNEEGALTVL QQFKESDLSH VQNKSAFLCG VMKTYRQREK QGSKVQESTK
GPDEAKIKAL LERTGYTLDV TTGQRKYGGP PPEDVFKGTQ PGIGTEVFVG KIPRDLYEDE
LVPLFESAGP IWDLRLMMDP LSGQNRGYAF ITYCNKDDAQ KAVKLCDNHE IRPGKYLGVC
ISVANNRLFV GSIPKNKTRE SILEDFGKVT EGLQEVILYH QPDDKKKNRG FCFLEYEDHK
SAAQARRRLM SGKVKVWGNP VTVEWADPVA EPDPEVMAKV KVLFVRKLAT AVTEELLEKT
FSQFGKLERV KKLKDYAFVH FEERDAAVKA MDEMNGKELG GEEIEIVLAK PPDKKRKERQ
AARQTTRNAG YDDYYYYPPP RMPPPGRGRG RGGRGGYAYP PDYYGYEDYY DDYYGYDYHD
YRGGYEDPYY GYEDVYSMRG RGTRPSRGGP PPPRARGAPP ARGRGGYAQR GPPLGGPRGG
RGGRGAPFQP QRGRGPRGAR GNRGGNVGGK RKADVFNQPD SKRRQTNNQQ NWGSQPIAQQ
PLQQGADYSG GEALRAAPLE
//
