ID A0A3P8SLU4_AMPPE Unreviewed; 705 AA.
AC A0A3P8SLU4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Forkhead box J2 {ECO:0000313|Ensembl:ENSAPEP00000013398.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000013398.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000013398.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000013398.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR AlphaFoldDB; A0A3P8SLU4; -.
DR STRING; 161767.ENSAPEP00000013398; -.
DR Ensembl; ENSAPET00000013756.1; ENSAPEP00000013398.1; ENSAPEG00000009557.1.
DR GeneTree; ENSGT00940000166343; -.
DR OMA; CKQPSPY; -.
DR Proteomes; UP000265080; Chromosome 7.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20024; FH_FOXJ2-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR045912; FOXJ2/3-like.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46078; FORKHEAD BOX PROTEIN J2 FAMILY MEMBER; 1.
DR PANTHER; PTHR46078:SF4; FORKHEAD BOX PROTEIN J2-LIKE; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 62..139
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 62..139
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 22..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 121..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 620..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..191
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..219
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..415
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..549
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..672
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 673..689
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 705 AA; 73936 MW; DF1155C8A60C252D CRC64;
MSSDLDSSLT SIDWLPQLGI SSLRSGRERG GGGGERRKDR GRERGDFLPS VPDPAPATCK
GKPPHSYATL IAMAIAAAPE RKLSLNDIYT WISDTFPYYS RAGRGWKNSI RHNLSLNKCF
RKVPRPQSDP GKGSYWTMDG PSEANQVRAL KRPYPEEEEE EEERKEVLQM ETPADRGPSP
PHPPHPPHPA SEASPQAASL SPPPCKQPSP YPPHPSASPS AAPIASINSF TPPQPPASTP
SAPPAPPSFS FPSAPPSVPP APPSFSFPST PPSVPPAPPA PPSFSFPSAP PSVPPAPPAP
PSFSFPSAPP SVPPAPPSFS FPSAPPSVPP APPAPPSFSF PSAPPSVPPA PPSFSFPSAP
PSVPPAPPAP PSFSFPSTPP SVPPAPPAPP SFSFPSAPPS VPPAPPGPPP SFSFTSSDPV
PVPSFSCVQN STLVAAPPIV SLNSSVDPSL RFTFDELHLP DLYASFKSLF KTMRERGGSQ
SDIVPLTFPS NDTTPLHTPT LLPMSPHPGP PCPPSSGPPS SAAHPGPSAP PGPLGPPSSG
PPGPPAVQHT VPPDWFSTTD SLKESFRIAS SLDWANIDLS GHPDLLESMR QAELCDWALD
PALFTSLCDS LNRFFTQRGM ITSPSNPPPT LASLTQPSPL PFPPNGAPPP RRVLGPNLQR
PQPTPPANTP AGLSPPSSRQ RPPLKSLHSN SEEIQDDFDW DSLLV
//
