ID A0A3P8SM61_AMPPE Unreviewed; 600 AA.
AC A0A3P8SM61;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Epsin 1 {ECO:0000313|Ensembl:ENSAPEP00000013513.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000013513.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000013513.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000013513.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the epsin family.
CC {ECO:0000256|ARBA:ARBA00010130}.
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DR AlphaFoldDB; A0A3P8SM61; -.
DR STRING; 161767.ENSAPEP00000013513; -.
DR Ensembl; ENSAPET00000013871.1; ENSAPEP00000013513.1; ENSAPEG00000009568.1.
DR GeneTree; ENSGT00940000160411; -.
DR Proteomes; UP000265080; Chromosome 7.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR CDD; cd16990; ENTH_Epsin; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12276:SF48; EPSIN-1; 1.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00726; UIM; 3.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50330; UIM; 2.
PE 3: Inferred from homology;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT DOMAIN 12..144
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 257..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..286
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..529
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 600 AA; 63788 MW; ABDD79247294AB91 CRC64;
MSTSSLRRQV KNIVHNYSEA EIKVREATSN DPWGPSSSLM SEIADLTYNV VAFSEIMSMV
WKRLNDHGKN WRHVYKAMTL MEYLIKTGSE RVAQQCRENI YAVQTLKDFQ YIDRDGKDQG
VNVREKAKQL VTLLKDEERL REERIHALKT KEKMAQTSSG EILQLWNQNN AWPQSSGEED
LQLQLALAMS KEEAEQTSKD PLEDAEFRYA LTLSKEMHQK EERLRRGDDL RLQMAIEESK
REKPKPEESA LMELSAVDPW GAPPAPAAAP GGSTGPSPPP TVPAPAASGP WDSAPTDPWG
VASPTSPTST DPWGGGAPPT VAPPPDPWGE TANRVNNVDP WGSSGEPPVA TCQHCSQSGG
SSSAWLHFFM SVPCLVSHFI LLCVSFHFCT GFTIRPLLFS WVLIPPVCLP GDPERRGSSA
AGCDSTGSPV PFNLSSLGSS LPVRKTPESF LGPNAALVDL DSLVSSKPKP KQPPPPSISS
SSAHNPFLQN TGQIRGVSPT PASSNPFGVA PPMTSISPQP SSLGLSGLRT SPVPPNPMLG
LVQPGGLSPM APPGPALLGP GAPPPQLILG GPSGPGGVMG AGGSVGGGGA AGASTNPFLL
//
