ID A0A3P8SML9_AMPPE Unreviewed; 458 AA.
AC A0A3P8SML9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Solute carrier family 2 member 13 {ECO:0000313|Ensembl:ENSAPEP00000013360.1};
GN Name=SLC2A13 {ECO:0000313|Ensembl:ENSAPEP00000013360.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000013360.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000013360.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000013360.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992}.
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DR AlphaFoldDB; A0A3P8SML9; -.
DR STRING; 161767.ENSAPEP00000013360; -.
DR Ensembl; ENSAPET00000013716.1; ENSAPEP00000013360.1; ENSAPEG00000009493.1.
DR GeneTree; ENSGT00940000155870; -.
DR OMA; ETGWRWM; -.
DR Proteomes; UP000265080; Chromosome 21.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR48020:SF12; MFS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48020; PROTON MYO-INOSITOL COTRANSPORTER; 1.
DR Pfam; PF00083; Sugar_tr; 2.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..408
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 458 AA; 51002 MW; F7B45DAAC70762F3 CRC64;
MTVPVYIAEA SPPHLRGQLV TVNTLFITGG QFTASLIDGA FSYLQRDGWR YMLGLSVLPA
VLQFMGFLFL PESPRWLIQR GLTQKARRVL SQIRGNQNID EEYDSIKNSI EEEEKDSGGD
GPVIWRMLTY PPTRRALLVG CGLQMFQQLS GINTVMYYSA TILQMSGVRD DRLAIWLAGL
TTLTNFLFTL LGVWLVERVG RRKLTLGSII GTCLSLSLLA VGFLISAQHT PPVTFHPLDP
AMANSTCSKY QLCEPCMLDP GCGFCYSENS SALLTSSCVP VNKASTEHAA WGRCSNSTLM
RDHTYWAYNY CPTSYSWLVL LGLMFYLAAF APGMGPMPWT INSEIYPLWA RSTGNACAAG
VNWTFNILVS LTFLHLAQYF TYYGAFFLYS SLALLGFVFI YGCLPETKAR RLEEIEALFE
NQLCSCGASD SDEGRQVEYI RVKGSNYHLS DNDASDVD
//
