ID   A0A3P8SNX1_AMPPE        Unreviewed;       285 AA.
AC   A0A3P8SNX1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Histone deacetylase 12 {ECO:0000313|Ensembl:ENSAPEP00000013862.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000013862.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000013862.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000013862.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A3P8SNX1; -.
DR   STRING; 161767.ENSAPEP00000013862; -.
DR   Ensembl; ENSAPET00000014225.1; ENSAPEP00000013862.1; ENSAPEG00000009872.1.
DR   GeneTree; ENSGT00940000166005; -.
DR   OMA; RTGFPWG; -.
DR   Proteomes; UP000265080; Chromosome 9.
DR   GO; GO:0004407; F:histone deacetylase activity; IEA:InterPro.
DR   CDD; cd09993; HDAC_classIV; 1.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   InterPro; IPR044150; HDAC_classIV.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625:SF8; HISTONE DEACETYLASE; 1.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT   DOMAIN          24..273
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
SQ   SEQUENCE   285 AA;  32239 MW;  7686868A6E788F6D CRC64;
     VRHESSGLPI IHHSRYVCEL PANHRFPMSK FPRVLHFLLK DQVVTDKQVW VPEIASKDLL
     SSVHTEDYLN NFINGKIDER EQRRTGFPWG TVLAAEVALQ RGLACSTAGG THHAFPSYGS
     GFCLLNDLAV AAKYVLNTSS TKRKILIVDL DVHQGDGTAF IFKEEPSVFT FSVHCGKNFP
     LRKQQSDLDI SVEDGVEDQE YLSTKEHLPW LLETFRPDLV LYDAGVDPHW DDELGRLRLT
     DQLYQRDLYM MKTVVSKGVP IATVIGGGYS RDIDKLALRH SIVHR
//