ID   A0A3P8SNX5_AMPPE        Unreviewed;       377 AA.
AC   A0A3P8SNX5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Major histocompatibility complex class I ZKA {ECO:0000313|Ensembl:ENSAPEP00000013661.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000013661.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000013661.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000013661.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MHC class I family.
CC       {ECO:0000256|RuleBase:RU004439}.
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DR   AlphaFoldDB; A0A3P8SNX5; -.
DR   Ensembl; ENSAPET00000014024.1; ENSAPEP00000013661.1; ENSAPEG00000009740.1.
DR   GeneTree; ENSGT01100000263531; -.
DR   OMA; ECICQSD; -.
DR   Proteomes; UP000265080; Chromosome 17.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003597; Ig_C1-set.
DR   InterPro; IPR011161; MHC_I-like_Ag-recog.
DR   InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR001039; MHC_I_a_a1/a2.
DR   PANTHER; PTHR16675:SF193; LOC571647 PROTEIN-RELATED; 1.
DR   PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR   Pfam; PF07654; C1-set; 1.
DR   Pfam; PF00129; MHC_I; 1.
DR   PRINTS; PR01638; MHCCLASSI.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..377
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018024991"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          209..298
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   377 AA;  42454 MW;  41A7C732321CB2D4 CRC64;
     MLLIAVLVLL GAQLTVHGEK HSLTYIYTAL SKPVGYPGIH EFTAMGLLDE KMIDYYDSEN
     QVKVPKQSWM KERLQKDYWD KGTQSRRSKQ QWFKVNIEIL MKRMRQNDSD IHVLQWMHGC
     VGDVQDDGSI KFNRGMDMYN YDGSEFLSFD DGNGVWVASV KSAEATKRKW DGVLVLKEYT
     KGYLENECIK WLKEFLDYGK KHLKEVSKPE VFLYTTKSRV ETNVVLNCLA TGFYPKDIIM
     QIKQNGRVLG KLDGLKSSNV RPNEDDTFQQ RDYVEILKSD VSTYSCRIIH KASDIDIEEV
     WAGDSNTGVI IGAVIVVLLL LVGVVLVVLK MTGKIGGAGR GARDINVAAI AMPAASPANG
     NAANASHVLL NRKYFPL
//