ID   A0A3P8SPL1_AMPPE        Unreviewed;       643 AA.
AC   A0A3P8SPL1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Fermitin family member 3b {ECO:0000313|Ensembl:ENSAPEP00000013901.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000013901.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000013901.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000013901.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the kindlin family.
CC       {ECO:0000256|ARBA:ARBA00008052}.
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DR   AlphaFoldDB; A0A3P8SPL1; -.
DR   STRING; 161767.ENSAPEP00000013901; -.
DR   Ensembl; ENSAPET00000014264.1; ENSAPEP00000013901.1; ENSAPEG00000009884.1.
DR   GeneTree; ENSGT00390000013444; -.
DR   OMA; RWLLQTH; -.
DR   Proteomes; UP000265080; Chromosome 13.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:InterPro.
DR   CDD; cd13205; FERM_C_fermitin; 1.
DR   CDD; cd17185; FERM_F1_KIND3; 1.
DR   CDD; cd01237; PH_fermitin; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR037843; Kindlin/fermitin.
DR   InterPro; IPR040790; Kindlin_2_N.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR037837; PH_Kindlin/fermitin.
DR   PANTHER; PTHR16160; FERMITIN 2-RELATED; 1.
DR   PANTHER; PTHR16160:SF1; FERMITIN FAMILY HOMOLOG 3; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF18124; Kindlin_2_N; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00295; B41; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT   DOMAIN          343..439
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
SQ   SEQUENCE   643 AA;  73592 MW;  E092D9BA4A046BB3 CRC64;
     MAAWDLSVTV EDLGSDAPPV TISVASDLHV GGVILKLVEK TQIKRDWSDH ALWWEQKQQW
     LLRTAWTLEK YGIHADARLL FMPQHKPLKL GLPNGITLRL RASFSCPVFQ TVMGICRMLN
     IRHPEELSLL RPVEEKKKKK DKDLAEEIYD LTEVPLSSVS RPCLYNGMPA HFVDSPQMEA
     IYKMLSVTQP PPAPEVIAKQ YRPASVVDKA HINGRWLDSS RCLMQQGIQE NDRLWLRFKY
     AAFYDIEPKY DVVRLTQLYE QARWAILLED VDCTEEEMML FGALQYHISK VAQSEPQMLS
     TNAAMDDLES ALMSLEVKME GENSSASELL ENMTAPELSD YLKLFRPKRL TLKGYKQYWF
     KFQDTSISYF KSKEESIGEP IQQINLRGCE VAPDVNVASQ KFLIRLLIPA PEGMNEVYLR
     CENEQQYAQW MAACRLASKG KSLADSSFQS EIQSIRSFLA MQKTNSHGNA PAGDESINTH
     SLVSPRYHKK YKPKQLTPRI LDAYQNVAQL SLTDALMRFL QIWQALPDFG LSYVVVRFKG
     SRKDEVLGIA PNRLIRIDLG VGDVVKTWRY NNMKQWNVNW DIRQMAIEFD GNVNIAFSCV
     TADCKIVHEF IGGYIFMSTR SREKSDTLNE ELFHKLTGGH EAL
//