ID A0A3P8SQA0_AMPPE Unreviewed; 458 AA.
AC A0A3P8SQA0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Bifunctional apoptosis regulator {ECO:0000313|Ensembl:ENSAPEP00000014141.1};
GN Name=BFAR {ECO:0000313|Ensembl:ENSAPEP00000014141.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000014141.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000014141.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000014141.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8SQA0; -.
DR STRING; 161767.ENSAPEP00000014141; -.
DR Ensembl; ENSAPET00000014518.1; ENSAPEP00000014141.1; ENSAPEG00000010071.1.
DR GeneTree; ENSGT00390000005386; -.
DR OMA; GNDQMPT; -.
DR Proteomes; UP000265080; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16497; RING-HC_BAR; 1.
DR CDD; cd09513; SAM_BAR; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR15898:SF21; BIFUNCTIONAL APOPTOSIS REGULATOR; 1.
DR PANTHER; PTHR15898; UNCHARACTERIZED; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 150..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..86
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 190..257
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
SQ SEQUENCE 458 AA; 53475 MW; C46FBEC146B4F21A CRC64;
MDMFQHMEWD SVDDGLGELM DEPTYLSESP QSKSTASSIS EHEFSCHCCY DILVNPTTLT
CGHNFCRHCL ALWWESSHKN ECPECREKWE GFPKINILLR DATDKLFSEV VQRRRAEIQA
NPKISRSLLA FQRYGDNLGR SRTNQHKGAG FFFSGVLSAL TCVAVMVLVY HWSYGVVEHD
LLISKPVSRW TPEEVVSWLE QLGPWAQLYR EPFQQENVNG RLLLMLGDEE LLKAPYSIEN
QAHRRAVLAE LDRVKALGVK PPQNLWEYKA ANAGKSLFLL YALKRSPRLT ILYLYLFDYS
ETFLPFLHTC CPAIAHIDQG VESRFLETQV KPSWRQWAEF LVKYCLLPYQ LIAEFAWDWL
AVHYWTSRFI IVNAMLLSVL EGCALWRLWT RARIRTLPRK MWNHLWKMLS QGFAFALLWP
FVPQFVCNCL FYWALYFSPI INIDLVVQQL MHPETQAL
//
