ID A0A3P8STN4_AMPPE Unreviewed; 1273 AA.
AC A0A3P8STN4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Nuclear factor of activated T cells 5b {ECO:0000313|Ensembl:ENSAPEP00000015613.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000015613.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000015613.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000015613.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8STN4; -.
DR Ensembl; ENSAPET00000016019.1; ENSAPEP00000015613.1; ENSAPEG00000011107.1.
DR GeneTree; ENSGT00940000155213; -.
DR Proteomes; UP000265080; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd07882; RHD-n_TonEBP; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR008366; NFAT.
DR InterPro; IPR015646; NFAT5_RHD_DNA-bd.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032397; RHD_dimer.
DR InterPro; IPR011539; RHD_DNA_bind_dom.
DR InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR PANTHER; PTHR12533; NFAT; 1.
DR PANTHER; PTHR12533:SF10; NUCLEAR FACTOR OF ACTIVATED T-CELLS 5; 1.
DR Pfam; PF16179; RHD_dimer; 1.
DR Pfam; PF00554; RHD_DNA_bind; 1.
DR PRINTS; PR01789; NUCFACTORATC.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS50254; REL_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT DOMAIN 244..423
FT /note="RHD"
FT /evidence="ECO:0000259|PROSITE:PS50254"
FT REGION 9..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 217..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 609..630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 669..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 796..830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 854..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 903..945
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 972..1019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1035..1060
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 732..779
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 13..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..694
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1273 AA; 138563 MW; 4370EDFD78F6BD11 CRC64;
MPSDFISLFS GDLDLNSPRS LYSKDAMSSS MTMEGPRSAF STSSSSTMHS SALVSDQNPA
HGSNVDPEDP RSSRVVPEVV AAESGNGSSS TGGNGRGSSE HGGGRGVTSQ EVQQHHQMTP
SKRRTILNIS PPPQDLFDDS RMSCQDEASL DSEQSNSIWM DDSLSNFSVM SSVSYNDNTE
VPRKSRKRTP RQRPGPKTAP AQEASMDVFD ADSAKGPHFV LSQLGPDSKT GAKGSSDDPQ
TANQKGGTLS MQFPQKSEGK ELKIVVQPET QHRARYLTEG SRGSVKDRTQ QSFPTIKLEG
VNEPVVLQVF VGNDAGRVKP HGFYQACRVT GRNTTACKEV DIEGTTVIEV ALDPSSNMTL
AVDCVGILKL RNADVEARIG VAGSKKKSTR ARLVFRVNIP RPDGSVLTLQ TPSSPILCTQ
PAGVPEILKK SLHSCSVRGG EEVFIIGKNF LKDTKVVFHE NVSDEKSWKA EAEIDMELFH
QNHLIVKVPP YQNPAVTSSV CVGIYVVTNA GRSHDVQPFT YTPDPAKNEV PVKKEAPSPV
KTCSFDEQIK VLDGALMSSM LPLVKREDVT PMEVTSNLQS SGVFKTGDLC PAQQNSDMTA
GHLNKSRAFP SSLAQPAGDP DKGQSPVFTN TEPLSTIQKQ DIATSSSFSV PADSLLQQSS
QQFLLEPRDG LRQERPGNTS GAVSRLCGEP ASQQQQLPMF PPDEVAQLEE AVRQLKAKGF
CNLPLQSDNS IAKQQQQQHI QHQQQIQKQQ IQQQQQQQIQ QQQFQQQQQQ QVLENLQQQL
FQSQIQMQCS MFQDASQGKN AERQGSSQGV VPNQGSLFQP TQQQQQQQQQ QQQQQQAALF
QQANDLLSIQ TNFLQQSSSH PSPPMFHNPS SLAETQDPQG ALFQKPSQEQ VQAALFQTTM
TVLQSPEQQP STPGLFLPQT PLPSQLSTSS SQQQQQQQQQ QQQQLAFLGA LQSSSPEPQS
VFQTQTQISP IQQRSPLEQQ QPSQPQPHTQ PAQPASMFQT ISPHPSANTL SPGQQQQQQA
GLLFCSNAMS TPDQASGLLF NSQGQMPPLT SSSLVSQEPQ NPSMLFSQAS MVTVNQQDRS
EPMALGNPTD PRQQVMFQEQ QPMQLGNSSN NRQEQPVGLF MPQSNMASLQ GGLAAQELAQ
SAMFASQNGV ANLQTTTSSP VQQPGTLFQT AVSGSINQPS RPQEPGLFLF TIQNECGQLM
NTPGNTLSDQ IIAISQSGQN QRESDAHIQS LLSQSLSQSG SVQSSMSASQ NMEKIDDLLV
SLQESGSNLT RSY
//
