ID   A0A3P8SVW1_AMPPE        Unreviewed;      1324 AA.
AC   A0A3P8SVW1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=SH3 domain and tetratricopeptide repeats 1 {ECO:0000313|Ensembl:ENSAPEP00000016659.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000016659.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000016659.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000016659.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   STRING; 161767.ENSAPEP00000016659; -.
DR   Ensembl; ENSAPET00000017118.1; ENSAPEP00000016659.1; ENSAPEG00000011916.1.
DR   GeneTree; ENSGT00530000063812; -.
DR   OMA; FTNEQQG; -.
DR   Proteomes; UP000265080; Chromosome 23.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR042772; SH3TC1/SH3TC2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR22647:SF3; SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR22647; SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00326; SH3; 1.
DR   SMART; SM00028; TPR; 4.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50002; SH3; 1.
DR   PROSITE; PS50005; TPR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}; TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          275..338
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REPEAT          1181..1214
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          419..459
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..28
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        419..443
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1324 AA;  147811 MW;  F3A8BCAB15F55EB1 CRC64;
     MSDQGPGSFR HRRESSADSQ HMTEKLETSG EHPPCGFSGD AASLKGTLTA CEENFPTALS
     VLLDVVTGPD QLPADEELQE MLRRKLRILQ ADSAEVNTLF MELSTHLVSI NSEEKAISVT
     FKTFEEIWKF TTYYTIGFLG HCMENLLLDQ MFWLSSLEED IAIKVSIQEE TLNLIYKGIL
     MQEGSFFASC SVNQMFDSST SGGDLYLEQG DIAQFEPPFL GSGWTVLCLA DGARGTAPKP
     SLKPVIPFHQ WFLKSCAESI LVGDGKPSCD FPLRFAKGTC LATAEYDAEG PDELSVAPGD
     HIIIVGVLVS CFDWFTGQKE ATGEVGLVKT SLVKPSTDIC DSADIFLDGE EWMFFSRQED
     KVIKESIAVL KTKSQNDIDC NYKLDTITYQ DLERKTSLSS SRTADTQQNE LKGNVQKLLD
     QGQGSSPDSI VTISRNPEDS VPATEAENPS PPRFTVHPVV EGKNNTENFI PLFSFLEGQN
     YKAEFGVLYG MTSELLASST FTGHSDDDEL IAFLGVARET ARKKRLFWPQ TRLCFLLGKL
     CTGRSKFSQA RVYFEESLNV PREVFTDLLL LASIYSNLAA IYLLQKNTES FFALTERLVA
     LVLGIPDCLK SLQDNSVLKY ILKKAVLSHN KMAEARACLL LAKHHWAHAE GVWAVPYLER
     LLVLCDEAQK TWSISPTDGY LTLGRLYSQL QLPHLSISPA RTASLQPSAM LSDCLGSLAL
     VLDNVNTQCD NTKQESTILP QVAPYLHQAL SLTMVHDVGN DHCYVLSHQL TVCLCQLFYK
     YKMVEHAIRH MHILINSNPS SQQVLIPAPE RNSALIWLAW LHIDNSQPNI ALEILDSVLA
     SMPEHCTTPQ EGVVLNMRGV ALRCMGDLRR AAESYQAAVD ICQEYEDMPN WAVAQANLGL
     LCLKAGAKGL AQRHLTEAVQ LFSELSEEGH EANFITVLLE LGQHSVKQQQ LDYGRGCYEW
     ALLLAIHANL SDCQLTATKH LCSLYGCENP NQAQCIIYSQ HQIQLLRATG DRRQEGDALE
     AIGKLYLTLG TERAYRAALD YTKSSLGIFI DLGCREKEAY GWLQAGNIYH LLGQTELVDI
     YVQAAQDVAL GTGDTIFILK LLEAAGDIFF NSCQDQDKAI TFYRDYALPI AVKSSSIHTR
     LRLCNKLTEV MLCLKLYGEA LEFAHTAVDI SVSLGECLNE RVAYHRLASL YHFLEQYELA
     EHYYLKTLTL CPTPLQFDEE TLYYVRLYQT LGDILFYDLK DPFDAAGYYH LALAAAMDLG
     NKRFQLQLCT RLATIYHNFL IDRELSLFFY QKARGYAAEL NVRRINISPD QQHSSTSQCK
     SAGQ
//