ID A0A3P8T1I0_AMPPE Unreviewed; 555 AA.
AC A0A3P8T1I0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=DAB adaptor protein 1a {ECO:0000313|Ensembl:ENSAPEP00000018199.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000018199.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000018199.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000018199.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8T1I0; -.
DR STRING; 161767.ENSAPEP00000018199; -.
DR Ensembl; ENSAPET00000018705.1; ENSAPEP00000018199.1; ENSAPEG00000013009.1.
DR GeneTree; ENSGT00940000158038; -.
DR OMA; FDEKTGX; -.
DR Proteomes; UP000265080; Chromosome 2.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR CDD; cd01215; PTB_Dab; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR048559; DAB1/2_SBM.
DR InterPro; IPR048561; Dab_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR PANTHER; PTHR47695:SF4; DISABLED HOMOLOG 1; 1.
DR PANTHER; PTHR47695; PID DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF21792; DAB2_SBM; 1.
DR Pfam; PF00640; PID; 1.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT DOMAIN 20..152
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 171..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..190
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 59280 MW; 6FC0213F87DF33DD CRC64;
MCVSAGQDRS EAALIRRFKG DGVRYKAKLI GLDEVTAARG DKLCQDSMMK LKGIAAGARS
KGEHKQKVFL TVSFGGIKIF DEKSGVLQHH HAVHEISYIA KDITDHRAFG YVCGKEGNHR
FVAIKTAQSA EPVILDLRDL FQLIYEIKQR EEMEKKAQKD KQCEQAVYQN GHKNTPHHHH
HHQHHQHHHY HDQPLHQEQT EPQQQQELEL AVANLIDLGL EMVTQNINQL EIFGDMSTPP
DITSPSTPAS PGNTLDPSQG LQPPTELFAP FNPASVPSGY VTMGAVPPGH WSQQAFAAQT
PLAFGVQSPL GPVAQVLPGG QPLIWGQANI FPATQQQWAA MAAGAFPPTA YLPAQPVGTL
PAAMFQTLTP VTTVTPAGES HSGAGASASA PSPSASSSPQ HGERAKKMGK EMFKDFQLAK
PPAMPSKKPE QPSLAGTSEA FSSYFSRVGT AQDTDDCDDF DISQMNLTPV TSTTPSTNSP
PTPAPRQSSP SKSSASHVSD PPTDATDPPT DDSFGEAEGS PSRSGEEDAA CGSGSPCPSE
TAEPSPDQAS PEAGS
//
