ID   A0A3P8TDD2_AMPPE        Unreviewed;      1070 AA.
AC   A0A3P8TDD2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Myosin phosphatase Rho interacting protein {ECO:0000313|Ensembl:ENSAPEP00000023555.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000023555.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000023555.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000023555.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8TDD2; -.
DR   Ensembl; ENSAPET00000024183.1; ENSAPEP00000023555.1; ENSAPEG00000016735.1.
DR   GeneTree; ENSGT00940000164958; -.
DR   Proteomes; UP000265080; Chromosome 19.
DR   CDD; cd13275; PH_M-RIP; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR039597; M-RIP_PH.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR17271:SF12; MYOSIN PHOSPHATASE RHO-INTERACTING PROTEIN ISOFORM X1; 1.
DR   PANTHER; PTHR17271; PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00169; PH; 2.
DR   SMART; SM00233; PH; 2.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   PROSITE; PS50003; PH_DOMAIN; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT   DOMAIN          5..112
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          417..513
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          114..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          174..231
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          263..406
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          516..578
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          594..655
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          696..723
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          766..1004
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        263..294
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        295..385
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        516..530
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        560..578
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        603..626
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1070 AA;  120718 MW;  B7D8535B2978233C CRC64;
     MIEAKPIYGG WLCLAPEGTD FDNPMQRSRK WQRRFFVLYE HGCLRFALDE SPSTLPQGTV
     NMNLCTDVID AEPKTGQKNS LCIITPDQEY FIRGENKEII NGWSEQLVVY PRTNKQNQKK
     KRKVEPATSL EPGPAKVAVT GSGIPETEKV PDSSSIIWQE ELNQREAEGA AVWTPADLPP
     GSLLPPAGDC ASVGQGSDAG SVNGDEADRG SLALHGSAPQ PPSDLLSPTG SCSSLGGVPR
     CLSPAPSDPF PSGSSLLSNG SHISGSVSSL DSDASGSTVT STDSHPANQR GGHSYSHHDT
     PRSRRLEAEA RKAERRSRFR SPDRQEREAV LSPERSRSGV IEKLEALELE NPEKMEVEES
     GRSGGRQGRS EHRRFHREEQ RRDVGQGLDF PSTLPPLRRA KSLDRRTTES VMTPDLLNFK
     KGWMVKLDEQ GQWKKYWFVL TDHSLRYYKD SIAEEASDLD GEIDLSTCYN VTEYQAQRNY
     GFQIHTQEGV HTLSAMTAGI RRNWIQAVMK NVRPSTAPDV ASSTEDHSSF SALEGLVRPD
     VTQDSPSSEA LSAERESTPG GIKSRARERR REGRSKTFDW AEFRPIAQAL AQQRAQEAES
     LQADMGELER NRRREERRKR YEFVTGSENT SEKGGGRTDY ESEEGVGHTD SLGPASLERQ
     QMVEEVIEEH WRQVEKTPIR EERRVPLPTT VQSTETAELE QLLENYKQGI EDLKAQLESC
     HQQLLDSNKH KQELELQLRT ALERDQDIRS GYISPATCER GFAAMEESHQ KVIDELQRKH
     QRELENLQEE KDRLLAEETA ATIAAIEAMK NAHRTELEKE LDKARKANNN AENADMEEIR
     RQHEEELCSF QREIEVLSEQ YSQKCLENAH LAQALEAERQ ALRQCQRENQ ELNAHNQELN
     NRLAAEITKM RSMTSEDGVG DTNNTIQGKE LYELEVMLRV KESEVQYLKQ EINSLKDELQ
     AAQRDKKYAT DKYKDIYTEL SIVKAKAERD LGRLRDQLQL AHEALGEASL EEVERGGYDI
     MKSKSNPDIL KMAAAAAKRS ERTMRSKSLK EGLTAEQRLH LFENKDTKEF
//