ID A0A3P8TDX0_AMPPE Unreviewed; 1049 AA.
AC A0A3P8TDX0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Uromodulin-like 1 {ECO:0000313|Ensembl:ENSAPEP00000022794.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000022794.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000022794.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000022794.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P8TDX0; -.
DR STRING; 161767.ENSAPEP00000022794; -.
DR Ensembl; ENSAPET00000023395.1; ENSAPEP00000022794.1; ENSAPEG00000016177.1.
DR GeneTree; ENSGT00940000159975; -.
DR OMA; QEHDCEP; -.
DR Proteomes; UP000265080; Chromosome 15.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0030414; F:peptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 4.10.75.10; Elafin-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 2.60.40.4100; Zona pellucida, ZP-C domain; 1.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR036645; Elafin-like_sf.
DR InterPro; IPR011489; EMI_domain.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR008197; WAP_dom.
DR InterPro; IPR042235; ZP-C.
DR InterPro; IPR001507; ZP_dom.
DR PANTHER; PTHR24050:SF19; NEPHRONECTIN; 1.
DR PANTHER; PTHR24050; PA14 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF00095; WAP; 1.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00217; WAP; 1.
DR SMART; SM00241; ZP; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57256; Elafin-like; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01187; EGF_CA; 2.
DR PROSITE; PS51041; EMI; 1.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..1049
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018308441"
FT DOMAIN 32..105
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT DOMAIN 182..221
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 385..423
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 761..983
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
FT REGION 492..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1049 AA; 112764 MW; AF5F32C67FB13305 CRC64;
MLSIWVTAAL LALYKGQYTI YLIPGNSLSP SGYHLCTYNE TRIVSFLVVH KVPYTESKPC
GGWLLWKTCT VTLYMLMHQT QYKTVTEQVT RCCDGYEQVG RYCALRESVN RSAEFAAKPG
SCPTADGLYP RSEDCELDIA CPGWQKCCQG LSSSACQDPK HNLHSKPHTC SDSHLTRHMS
ADVDECAHSA LRQCSLQAHC NNTVGSYQCV CHQGYTDVDP TPPSISSLLA ANVTGTSFSV
CWSTQSQTNQ THKVVLSKDS KVILSWETRQ TMIEVKGLQP AMLYHVSVTP HACGSDGVTL
HMSACFICQQ QLYQSFSPEM RSMVDSGQVK IEIRGFSPGS VVVNFTIIFT PSQSQNISNV
STALLHSLMN ISQYTVDENN TSINDFNECA SLENDCSFWA TCINIWASYM CVCQDGFTDN
NPERPGRACQ GRPTTPALTT SIFSTASTTP VSQLKPSTSD PTITTVITPA IATVIITSET
VSTTISTSAQ DTTISTTTNP TPAPTKPTTA PTITAIIPTT TPSIPTASSS PTTTTAHAIV
NTAPTTTTST PTISAPTTVT APPTVVTTAP VTTISTLTAT STPVTTTTTP TTAFTTPVTT
SASTTTAAPT TTTTAPAVTT TAPTTSINFT PTTSITLTTT STTTAIVTAL VMTTAATVPT
TAQTTTTTPA TTTITPTTIT TTPTITLYNP TTTTTMPTTT TSAIPTATTT IPTNANTTST
TTTTTPTTTT TTPTTTTNTP TTTTTPRVAN NGSMQGSLSV QCRVAAITVT MAKDFLLSSK
IQESALYLGM RGCGVNGGND THVQLTVAWN ECDTRLVDNI TFTLENSNRS PESCSAVHIL
SSICRYDMIK DVIMGLGSFQ VTVQLMNGSV PLPYNYSLSS EQAVVVEVRL NTSSEQLKVV
INKCWATPSR SPCDNRPLPF KFHNINCSMN SYTKVLINGN SSTSRVSVQI FSIVNLNVIY
LHCQVQICIQ IGSDTCVPVS TFYSTKTTLS LAEYKRTRTV VGIFKEDIII HDIVILSCRT
VYKEQHVLRK LLEQHLTLLE NFTYLVFNT
//
