ID   A0A3P8TFB6_AMPPE        Unreviewed;       767 AA.
AC   A0A3P8TFB6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Si:ch211-136a13.1 {ECO:0000313|Ensembl:ENSAPEP00000022037.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000022037.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000022037.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000022037.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the HHIP family.
CC       {ECO:0000256|ARBA:ARBA00010658}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR   AlphaFoldDB; A0A3P8TFB6; -.
DR   Ensembl; ENSAPET00000022620.1; ENSAPEP00000022037.1; ENSAPEG00000015558.1.
DR   GeneTree; ENSGT00940000164056; -.
DR   OMA; IHINGEW; -.
DR   Proteomes; UP000265080; Chromosome 9.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   Gene3D; 3.10.250.10; SRCR-like domain; 1.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR018143; Folate_rcpt-like.
DR   InterPro; IPR012938; Glc/Sorbosone_DH.
DR   InterPro; IPR011041; Quinoprot_gluc/sorb_DH.
DR   InterPro; IPR001190; SRCR.
DR   InterPro; IPR017448; SRCR-like_dom.
DR   InterPro; IPR036772; SRCR-like_dom_sf.
DR   PANTHER; PTHR19328; HEDGEHOG-INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR19328:SF58; HHIP-LIKE PROTEIN 1; 1.
DR   Pfam; PF03024; Folate_rec; 1.
DR   Pfam; PF07995; GSDH; 1.
DR   Pfam; PF00530; SRCR; 1.
DR   PRINTS; PR00258; SPERACTRCPTR.
DR   SMART; SM00202; SR; 1.
DR   SUPFAM; SSF50952; Soluble quinoprotein glucose dehydrogenase; 1.
DR   SUPFAM; SSF56487; SRCR-like; 1.
DR   PROSITE; PS50287; SRCR_2; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW   ProRule:PRU00196}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..767
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018170473"
FT   DOMAIN          664..767
FT                   /note="SRCR"
FT                   /evidence="ECO:0000259|PROSITE:PS50287"
FT   DISULFID        736..746
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ   SEQUENCE   767 AA;  86249 MW;  811836CDE743AFFB CRC64;
     MWPFPTFSRH LLLPVLLLLL HAWWGCCHPQ CLDYKPPFQP HQPLVFCKEY SKFGCCDVEK
     DEQISHRFYT IMENFDHSGY VTCGRYIRSI LCQECSPYAA HLYDAEDANT PMRMLPGLCG
     DYCSDYWHQC RYTLGLLLED SGSPQQFANL TATIEEDRRK FCDFLELKDQ QYCYPNVLMN
     TELNANLGLV REDPKGCLEL CLQEVANGLR NPVAMIHADD GTHRFFVAEQ LGYVWVYLAN
     GSRIDRPFLN LTQAVLTSPW AGDERGFLCI ALHPRFTTVR KAYVYYSVSV KKQERIRISE
     FTLSVHDDNQ LDHSSERYLL KYVVEPASNH NGGQLLFGHD GYLYIFIGDG GRAGDPFGKF
     GNSQNKSVLL GKVLRIDVDN NDDGAPYSIP SDNPFLGEKE TRPEIYAYGV RNMWRCSIDR
     GDPATGAGRG RMFCGDVGQN KYEEVDLIVK GGNYGWRAKE GFSCYDRKLC QNSSLDDILP
     IFAYPHKLGK SVTGGYIYRG CQMPNLNGLY IFGDFMSGRL MSLKENTTTG EWQYTEICMG
     RGQTCRFPKL IDSHYKYIIS FAEDEAGELY FLATGVPSAT ARTGVIYKIV DPSRRAAPGK
     CSIKPSPVKI KGKLVHFHPK EGKLWIGEKL ESAGEGNQVY KKPRGKGRGY KKGRDGRRLR
     AGSVRLVSTD GLLDRGRVEI FLRGEWGTVC DDLFSAKAGS VVCRQLGFTK ALAVMKRAAL
     GEADSSVRIL LDDVECEGGE RSLLACKRSR VGKHNCSHGE DVGVICG
//