ID A0A3P8TL38_AMPPE Unreviewed; 308 AA.
AC A0A3P8TL38;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=C1q and TNF related 2 {ECO:0000313|Ensembl:ENSAPEP00000025396.1};
GN Name=C1QTNF2 {ECO:0000313|Ensembl:ENSAPEP00000025396.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000025396.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000025396.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000025396.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR AlphaFoldDB; A0A3P8TL38; -.
DR STRING; 161767.ENSAPEP00000025396; -.
DR Ensembl; ENSAPET00000026066.1; ENSAPEP00000025396.1; ENSAPEG00000018084.1.
DR GeneTree; ENSGT00940000159591; -.
DR OMA; MPGPCSC; -.
DR Proteomes; UP000265080; Chromosome 13.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427:SF28; COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 2; 1.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 2.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..308
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017946077"
FT DOMAIN 158..294
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 52..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..96
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 308 AA; 32409 MW; 2F726011B7008BC1 CRC64;
MPMGHNSSTV AIMLQMCVMI CLLSVVVSQS TNSSSKKGRN ITIHSSQLVC SLPGPAGPAG
NPGAPGSQGT MGPMGPPGKD GPDGKDGEKG EKGDRGNPGR PGNQGKPGVK GREGYIGKAG
PRGLKGLRGA PGVAGKRGQK GELGDMGQQG APGGCNCGST ARSAFSVAVT KSYPKERMPI
RFSRILLNEG NHYNTSSGKF VCAIPGVYYF TYDITLANKH LAIGLVHNGQ YKIKTFDANT
GNHDVASGST VLQLQQSDQV WLQIFYSEQN GLFFDPFWTD STFTGFLIYA DQDFLNEADN
KANAQADS
//
