ID A0A3P8TNN1_AMPPE Unreviewed; 686 AA.
AC A0A3P8TNN1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=U3 small nucleolar ribonucleoprotein protein MPP10 {ECO:0000256|PIRNR:PIRNR017300};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000026589.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000026589.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000026589.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Component of the 60-80S U3 small nucleolar ribonucleoprotein
CC (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal
CC RNA processing. {ECO:0000256|PIRNR:PIRNR017300}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|PIRNR:PIRNR017300}.
CC -!- SIMILARITY: Belongs to the MPP10 family.
CC {ECO:0000256|ARBA:ARBA00029455, ECO:0000256|PIRNR:PIRNR017300}.
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DR AlphaFoldDB; A0A3P8TNN1; -.
DR STRING; 161767.ENSAPEP00000026589; -.
DR Ensembl; ENSAPET00000027300.1; ENSAPEP00000026589.1; ENSAPEG00000018904.1.
DR GeneTree; ENSGT00390000011359; -.
DR OMA; HFAEDFG; -.
DR Proteomes; UP000265080; Chromosome 1.
DR GO; GO:0034457; C:Mpp10 complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005732; C:sno(s)RNA-containing ribonucleoprotein complex; IEA:UniProtKB-UniRule.
DR GO; GO:0055123; P:digestive system development; IEA:Ensembl.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR012173; Mpp10.
DR PANTHER; PTHR17039; U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10; 1.
DR PANTHER; PTHR17039:SF0; U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10; 1.
DR Pfam; PF04006; Mpp10; 1.
DR PIRSF; PIRSF017300; snoRNP_Mpp10; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR017300};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|PIRNR:PIRNR017300};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|PIRNR:PIRNR017300};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552,
KW ECO:0000256|PIRNR:PIRNR017300}.
FT REGION 107..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 460..495
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 107..136
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..190
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..240
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..318
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..336
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..381
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..597
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..619
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 686 AA; 77781 MW; BF493144106C47E1 CRC64;
MATGDVWSVL EECVKKINAN TAQPEKFLSL QDGVAADFTS LTKTLYDLHK AQEPADYQGS
PLAQLVVEDF DEEQIWQELE LQNNAVLKHF QNAIDEAVSD ETLTVLEDEE EEDEEENGQE
EGATDDENDA EEQEEEPPIP GQSKKKAVEA EDGADAYSEE DSDLDFDVDA LEKREKQKKE
IGRKGSKTKV VPSEVDDTFF KLSEMESFLD DMDKREGKED EDEDDVDYFQ DLPSDEDEDA
DLVTILSTKK QQKHTVKSSR NLKYKDFFDA VDGAPAKTDD QSDGEDDSMD GSQEEDEEEM
DDEEDEYDGE EEGDDDDEER SQSKASQKKV TFNLSEDEDS EGEEMEDIFG GKAPSSAKSE
SKSSFEKRQE KMAKQIEGLE KAALGEKPWQ LSGEATAQTR PENSMLEEDV EFEQASRRAP
AITEETTLQL EDIIKQRIKD QAFDDVVRKE KPKEEVFEYK KRLTLDHEKS KQNLAEIYEQ
EYLKQTQQKT EEEENPGHVE IQKLMDTLFL KLDALSNFHF TPKPPVPEVK VVSNLPSITM
EEVAPVGTSD ATLLAPEEIK AKNKAGDVLG TTEKTSTDKK RERRHKKKVK HLKIKEKERR
QKLKEASQTG EKKKLSKAEV TENLKKLTKG GKATILKDEG KDKALRSSQA FFSQLQDQVK
SQIKSTKDPS SKKKKSKELS VSKLKL
//
