ID A0A3P8TTC2_AMPPE Unreviewed; 1764 AA.
AC A0A3P8TTC2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=SAP domain-containing protein {ECO:0000259|PROSITE:PS50800};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000028304.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000028304.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000028304.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 161767.ENSAPEP00000028304; -.
DR Ensembl; ENSAPET00000029053.1; ENSAPEP00000028304.1; ENSAPEG00000020100.1.
DR GeneTree; ENSGT00710000106790; -.
DR Proteomes; UP000265080; Chromosome 10.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd12432; RRM_ACINU; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR034257; Acinus_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR032552; RSB_motif.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR46589; APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; 1.
DR PANTHER; PTHR46589:SF1; APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; 1.
DR Pfam; PF16294; RSB_motif; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT DOMAIN 14..48
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 100..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 689..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 757..1286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1299..1379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1525..1561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1586..1634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1661..1764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..191
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..211
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..285
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..309
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..871
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 941..956
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 983..997
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1011..1028
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1032..1094
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1095..1125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1126..1140
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1154..1172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1183..1227
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1231..1248
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1269..1285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1308..1326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1342..1373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1600..1614
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1615..1634
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1661..1741
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1764 AA; 201813 MW; CEBF01B521EC8DDD CRC64;
MADLEDVTLD GRPLQSLRVA DLKAALEERG LSKSGQKNTL IKRLKGALML ENLQRTSTPH
IGLQPNSHIG EEMSQNSFIK QYLAKQQELL RQRLEREARE AYETNDQDDH AEVNNSTSCP
PPAQDATPAL AEQHKPPGPS GGDGLFGAVN EGQGNRNQEA DMSNPPPSGS VAMRVPGIEH
RPERGSASSE VAGDSDDDDS EDGDEDGDDD DWDNSARRRN LREPARMPTA RERSGASCQP
QQQHIPSLLS PQLRQPTPPP SPPPELSFPL PDTPKQSPPS PDVAPARGSP STSSSGSSSS
DSRSSSPEPQ RSGHAERKPG PLTLLARKME SEGAFSGASW HGADGEGDRQ DSSSPSAAAF
PGRGPPEGLV SAIAHTAKTA GHVPFPMIPG TNQGVTGAHL AHIQAPVSVL KATAAEERDR
EMELEMEREK ALELERQEKL RKLEQERAME EERQRALALE REREERERAL ERERFERQQA
LEREEREKAL QRERELALER ERQEREQALA KEREEREQAL ARERALELER QRALEQERLQ
REKEEREKRE REERERAMEL ERAKALERER EEREQALEQE RIERERALEA ERKERERIER
EKALEQERLE KERLEREKAE QERIEREKAL ERERIERERA LEQERIEREK ALERERIERE
KALEQERLER EKALEKERLE REKALEKERL EQERREKERL EQERREKERL EQERREKERL
EQERREKERL EQERREKEKI ERERALEQER IEREKALERE REEKEKAERE AALERERMEK
ERAEKERKER LEREKALEQE KLERARALEK ERKEKERALE QEKAMTLERE RLEKEKAMQK
EREEQERAQE QEKERARMAE RERESHLPPT KRGREVGLTP LPTPPPLSTG PATKTSTEAG
EQEDAPVSRS EAQAAESGAP MSPTPLSPHS SFKKFRFFRD SPLQPQTSST SMVIKRPRTF
SDCPQPRVSP VSSPTSVGER PLEEHQPSTE QEDQQIHTNR EVAAGPPGSA RTPSEKQTAV
STALGQSPKK ERATRLVLEE KEQAASAKTE QAAKDSIKKA KEVDEIKSSS SSVDAKERRG
RDAEKEEKRT RQRSSSNDSS SSESDSGSSS SRSSGSSTSS QEKTRSTSRG RQEGKPERDS
PVKAQAQGLK ETPEASPCKR ETSTEKNNTT ADSRSKKLFT EAPTTGETHR KRKDSEEAEI
KDKQRQVKDT AMADPEKLPE TSEETPKAFS ARKISLSSSK SSPGAGSAEG DQESAAVAGR
KRRWGSSTAV TAKKPSISIT TDSLKSLIPD IKPCLGQEAV VDLHPEETVL SGAEDEDRER
SDQDLQIRRT VTQVVPLENQ ENGQKEAKRS RHEELEEEDL RGDRERTKAH EEPMDSSISG
AVETQSPTYI SHDVEINTVT PSDTLIRRSI SQQKTGVSIT IDDPVRTARQ PSPPRGKVSA
IVHVCNLVRP FTLGQLKELL SRTGTLVEEG FWIDKIKSHC YVTYSSIEEA VATRAALHGV
KWPQSNPKVL SVDFCQQDEL DFHKGLGAAD RPGAEDQGPG SGRGRTLGLP SLLPERDQWA
EREREMERRE RARAEREWDR DKVREFGKPG EEKEGGPRRS RSRERRRKER GKSKEKKTEK
KEKAAEDPPA KLLDDLFRKT KAAPCIYWLP LTEEQFLQRE AARAERMKER EKRRKEQEEE
EERKERMKAA GGTTGDRSEG EKDKDRDRER DRDRGRDRHR DRERERERER ENDKRRDGYR
RPGGSGAGGG RRSRSRSEPR ERRR
//
