ID   A0A3P8U1R9_AMPPE        Unreviewed;       471 AA.
AC   A0A3P8U1R9;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=RAP1 GTPase activating protein 2b {ECO:0000313|Ensembl:ENSAPEP00000029252.1};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000029252.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000029252.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000029252.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8U1R9; -.
DR   STRING; 161767.ENSAPEP00000029252; -.
DR   Ensembl; ENSAPET00000030035.1; ENSAPEP00000029252.1; ENSAPEG00000020770.1.
DR   GeneTree; ENSGT00940000165230; -.
DR   OMA; QEHLHVI; -.
DR   Proteomes; UP000265080; Chromosome 15.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 6.10.140.210; -; 1.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR15711:SF72; ZGC:175145 PROTEIN; 1.
DR   Pfam; PF21022; Rap-GAP_dimer; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080}.
FT   DOMAIN          178..394
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   REGION          39..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..73
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   471 AA;  53848 MW;  EEC371E3E338455A CRC64;
     LFCLFQDDYI PYPRIEEVLE RGAPYPQVIL PQFGGYWIED PEAPPPTSSE SRGEGEEEEA
     GERREEDTPR GDYGYQLEEI NEAARAYRKH FLGREHLNFS CSASSLGNLL LSVRHEEDGE
     HEFISSVFRS RVKSVYHRLS LSELPDIPSV PELAKLLCDE AAGLRFTPVL YPKASRLIVN
     YDEHDVNNTF KFGVIYQRFG QMSEEELFRN NEETPAFTEF LQLLGDTVEL QDFKGFRGGL
     DVSHGQTGSQ SIYTVHRQQE IMFHVSTKLP FTEGDAQQLQ RKRHIGNDIV AVVFQEEATP
     FVPDMIASNF LHAFILVQVE EPCSDNTSYK VSVTAREDVP PFGPPLPNPA VFKKGQEFRE
     FLLTKLINAE LACYKSDRFA RLEERTRAAL LDSLHDELQR RSQCMLGLMS GLEEEGRAEN
     GHAHGGLLES IKVCLILFPV FFPSFCIIRY FNLTSQHHFF YNHHQIIVPA F
//