ID A0A3P8U550_AMPPE Unreviewed; 686 AA.
AC A0A3P8U550;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Nucleolar protein 10 {ECO:0000256|ARBA:ARBA00015517};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000032464.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000032464.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000032464.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the WD repeat NOL10/ENP2 family.
CC {ECO:0000256|ARBA:ARBA00005264}.
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DR AlphaFoldDB; A0A3P8U550; -.
DR STRING; 161767.ENSAPEP00000032464; -.
DR Ensembl; ENSAPET00000033323.1; ENSAPEP00000032464.1; ENSAPEG00000023044.1.
DR GeneTree; ENSGT00390000007900; -.
DR OMA; CFDSEVT; -.
DR Proteomes; UP000265080; Chromosome 18.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR040382; NOL10/Enp2.
DR InterPro; IPR012580; NUC153.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR14927:SF0; NUCLEOLAR PROTEIN 10; 1.
DR PANTHER; PTHR14927; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 478..504
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 523..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..578
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..665
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..686
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 686 AA; 79602 MW; CBEBEBA31C9548E0 CRC64;
MQISSVNDVK IYNLSHGKSL PEWLSDRKKR QLQKKDVDIQ RRIELIQDFE MPTVCTSIKV
SRDGQFILAA GTYKPRIRCY DTYQLSLKFE RCLDSDVVAF DVLSDDYSKL VFLHYDRYVE
FHSQHGHYYK TRIPKFGRDF SYHYPSCDLY FVGASSEVYR LNLEQGRFLN SLQTDAVENN
VCDINPVHHL FATGTSEGRV ECWDPRVRNR VGLLDCALSS LIQGLPSISA LKFHGSLNMA
VGTSTGQVLL CDLRSSQPLL VKDHFYNLPI NSLNFHDQLD LVVSSDSKII KIWNKDTGKL
FSSIQPQVNI NDVCMYPNSG MLFTANEDPK MNTFYIPALG PAPRWCSFLD NLTEELEESP
ESTVYDDYKF VTRKDLDNLG LSHLVGSSLL KAYMHGFFMD IRLYHKVKSM ANPFAYEEYR
KDKIRQKIEE SRTQRVQVKK LPKVNKELAL KLMEEGDDEA ELTSRTKKGK ALPSILGDDR
FKVMFENPDY QVDEQSDEFR LLNPIVSKVG QKWKKKLRLL AQQDVADDEE EPEGRASSEE
ESSDDDKSWV EEVREQRRLL RQEDRDRRRQ ERKEADRNTV LQPQFYQIKA GEEFRSFNDM
AHKQKLQKAS LEDRLKMEEY SGVSNVADTA VGSKQLTFTL KKSEQQRKQQ QAERDHHEER
KKLRRSAGHL SSRRGRGWGG RGRGRR
//
