ID   A0A3P8U5G2_AMPPE        Unreviewed;       585 AA.
AC   A0A3P8U5G2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Amino acid transporter {ECO:0000256|RuleBase:RU361216};
OS   Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000032574.1, ECO:0000313|Proteomes:UP000265080};
RN   [1] {ECO:0000313|Ensembl:ENSAPEP00000032574.1, ECO:0000313|Proteomes:UP000265080}
RP   NUCLEOTIDE SEQUENCE.
RA   Lehmann R.;
RT   "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT   of the orange clownfish Amphiprion percula.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPEP00000032574.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU361216}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361216}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000256|RuleBase:RU361216}.
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DR   AlphaFoldDB; A0A3P8U5G2; -.
DR   STRING; 161767.ENSAPEP00000032574; -.
DR   Ensembl; ENSAPET00000033437.1; ENSAPEP00000032574.1; ENSAPEG00000023125.1.
DR   GeneTree; ENSGT00940000159972; -.
DR   OMA; TDVFLRM; -.
DR   Proteomes; UP000265080; Chromosome 2.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:1902475; P:L-alpha-amino acid transmembrane transport; IEA:UniProt.
DR   Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR11958:SF67; EXCITATORY AMINO ACID TRANSPORTER 4; 1.
DR   PANTHER; PTHR11958; SODIUM/DICARBOXYLATE SYMPORTER-RELATED; 1.
DR   Pfam; PF00375; SDF; 1.
DR   PRINTS; PR00173; EDTRNSPORT.
DR   SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR   PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361216};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW   Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|RuleBase:RU361216};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361216};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361216};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361216}.
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        127..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        162..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        286..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        326..347
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        359..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   REGION          36..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   585 AA;  64239 MW;  FF310E3FF7243463 CRC64;
     MTNPLFFLPP VSHETCLLDQ VLELIMNEKP PTSASLFLNE DADKPPLPDR GDLRRRLRRA
     MERRASSMKE RMSSVSRDNV RSFLRRNLFV LFTVAAVALG VILGFALRPH NLSLREIKYF
     AFPGELLMRM LQMLVLPLII SSLVTGISSL DSKASGKMGV RAVVYYMVTT LVAVFIGIVI
     VIIIRPGKGS RDSPVAKTGN IEPVQAADAF LDLIRNMFPP NLVEACFKQY KTMYKKIIRT
     RNVTVTLNLT ESLNMTESNL NLSRVLHTIQ ETVEETVPVS GSSSGVNALG LVVFSICFGL
     VIGNMKQQGQ ALRDFFDCLN EAIMRLVAVI IWYAPVGILF LIAGKIVEMK DLAEVGGQLA
     MYTVSVIVGL LIHGLFILPL LYFLVTRRNP YSFIGGLLQA LITALGTSSS SATLPITFRC
     LEENNYVDKR VTRFVLPVGA TINMDGTALY EAVAAIFIAQ VNDMDLNFGQ ILTISITATA
     ASIGAAGIPQ AGLVTMVIVL TSVGLPTEDI TLIIAVDWFL DRLRTTTNVL GDSLGAGIVE
     HLSHGELQNQ DAEVRNSVIE DNEKPYQLIC QENDVVNHLN SETTM
//