ID A0A3P8U918_AMPPE Unreviewed; 580 AA.
AC A0A3P8U918;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Formin binding protein 1b {ECO:0000313|Ensembl:ENSAPEP00000033271.1};
GN Name=FNBP1 {ECO:0000313|Ensembl:ENSAPEP00000033271.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000033271.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000033271.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000033271.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cell cortex
CC {ECO:0000256|ARBA:ARBA00004544}.
CC -!- SIMILARITY: Belongs to the FNBP1 family.
CC {ECO:0000256|ARBA:ARBA00009426}.
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DR AlphaFoldDB; A0A3P8U918; -.
DR Ensembl; ENSAPET00000034143.1; ENSAPEP00000033271.1; ENSAPEG00000023547.1.
DR GeneTree; ENSGT00950000183047; -.
DR Proteomes; UP000265080; Chromosome 16.
DR GO; GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd07676; F-BAR_FBP17; 1.
DR CDD; cd11629; HR1_FBP17; 1.
DR Gene3D; 6.10.140.470; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR037449; FNBP1_F-BAR.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR PANTHER; PTHR15735:SF13; FORMIN-BINDING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS51860; REM_1; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..264
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 353..430
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 513..574
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 293..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 360..387
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 446..485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 67000 MW; 342C4E0CF83E9397 CRC64;
MSWGSELWDQ FDNLEKHTQW GIEFVEKYTK FVKERSEIET NYAKQIRNLS KKYQPKKNSR
EEEESKYTFC KAFLTTLNEL NDYAGQHEVI AENLTSQIIG ELTRYLTELK AERKSHFHDG
RKAQQHIESS WKQLESCKRR FERDCKEADR AQQYFEKMDA DINVTKADVE KARQQAQMRH
QMAADSKGDY SSYLQKFNQE QNEHYYTVIP NIFQKLQDME ERRIERIGVC MKTFSDVDRQ
VLPIVGKCLD GMTKAAESIE PKTDSKQVVE SYKSGFEPPG DVEFEDYGQT MKRTASDTSL
SNSREGKEKP AGKSKGKLWP FIKNKNKLSL KLITLNSQVR NLIEGSGPED FSHLPPEQRR
KKLQGKLDEL NKDIQKEMDQ RDALTKMKDV YVKNPQMGDP ASVDPRLSEI GQNIEKLQFE
VQKFEGWLAE VEERMPSKSD SHRRSGLYET QNNTTVSNNC AQDRESPDGS YTEEQNSETQ
VKANPNPNPN PNPNPTSSTP EFDDEFDDEE TLPTIGTCKA LYPFEGHNEG TISVAEGELL
YVIEEDKGDG WTRVRRNEDE EGYVPTSYVE VFLETNAKDS
//
