ID A0A3P8UFA0_AMPPE Unreviewed; 501 AA.
AC A0A3P8UFA0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Natriuretic peptide receptor 3 {ECO:0000313|Ensembl:ENSAPEP00000034278.1};
OS Amphiprion percula (Orange clownfish) (Lutjanus percula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=161767 {ECO:0000313|Ensembl:ENSAPEP00000034278.1, ECO:0000313|Proteomes:UP000265080};
RN [1] {ECO:0000313|Ensembl:ENSAPEP00000034278.1, ECO:0000313|Proteomes:UP000265080}
RP NUCLEOTIDE SEQUENCE.
RA Lehmann R.;
RT "Finding Nemo's genes: A chromosome-scale reference assembly of the genome
RT of the orange clownfish Amphiprion percula.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPEP00000034278.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR AlphaFoldDB; A0A3P8UFA0; -.
DR STRING; 161767.ENSAPEP00000034278; -.
DR Ensembl; ENSAPET00000035169.1; ENSAPEP00000034278.1; ENSAPEG00000024339.1.
DR GeneTree; ENSGT00440000033872; -.
DR OMA; ETRVMEH; -.
DR Proteomes; UP000265080; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR001170; ANPR/GUC.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR44755:SF11; ATRIAL NATRIURETIC PEPTIDE RECEPTOR 3 ISOFORM X1; 1.
DR PANTHER; PTHR44755; NATRIURETIC PEPTIDE RECEPTOR 3-RELATED; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR00255; NATPEPTIDER.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265080};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..501
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018278217"
FT TRANSMEM 439..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..389
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
FT REGION 479..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 501 AA; 56788 MW; 0419E02B5D470B9A CRC64;
MPYFTTLCVY FLMVLNPVMT NTITEDIEVL VFLPQNNSFL FSYARVAPAI RYAQQKMKAD
GNQYSGFHFN IHFENSDCVN DALFTLLDRS CGQKPDLILG PVCEYEAAAV VRLASYWKIP
VISAGALATG FGNKKTEFSH LTRIAPSYVK MAETFTAMFE HFTWKSALLV YEDDKEERNC
YFTLEGVYHL MADYTIKTYQ FSEEDPLNVD DILQNIYDIE VMIMCMGADK IREIMLAAHR
RQLTSGNYMF FNVELFNSSS YGNGSWKRGD KYDNDARQAY ASLNTVTLLR TVKPEFENFL
IEMTKSIEKA GLNDCKDCGN VNMFVEGFHD AMLLYAIALH EAMKSGYSKK NGTEITSRMW
NRTFEGIAGQ VSMDVNGDRN GDFSLMAMTN VEAGAYEVVA NYFGVNGTFQ LLPAFNIDHF
TLKGRHKEYP EMPDKACGLG VSALTGVIVG AVLGTVMLIA FYFFRKNYRI TIERRTHGEE
CDSGKHRQLR EDSIRSNFSA A
//
