ID A0A3P8UJ53_CYNSE Unreviewed; 449 AA.
AC A0A3P8UJ53;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4-like {ECO:0000313|Ensembl:ENSCSEP00000001879.1};
GN Name=CACNB3 {ECO:0000313|Ensembl:ENSCSEP00000001879.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000001879.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000001879.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000001879.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8UJ53; -.
DR STRING; 244447.ENSCSEP00000001879; -.
DR Ensembl; ENSCSET00000001911.1; ENSCSEP00000001879.1; ENSCSEG00000001270.1.
DR GeneTree; ENSGT00950000182837; -.
DR InParanoid; A0A3P8UJ53; -.
DR OMA; LVQCPPV; -.
DR Proteomes; UP000265120; Chromosome 10.
DR GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR046937; CAB1-4_N_A-dom.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR000584; VDCC_L_bsu.
DR PANTHER; PTHR11824; VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT; 1.
DR PANTHER; PTHR11824:SF18; VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-4; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF12052; VGCC_beta4Aa_N; 1.
DR PRINTS; PR01626; LCACHANNELB.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 162..340
FT /note="Guanylate kinase/L-type calcium channel beta
FT subunit"
FT /evidence="ECO:0000259|SMART:SM00072"
FT REGION 13..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 449 AA; 50149 MW; 8408D905E29B8EC3 CRC64;
SFCCLFLHSQ VSGSADSYTS RPSDSDLSLE EDQEASRREA ERQAQLQLER AKSKPVAFAV
KTNVSYCGAL DEDCPVQGAA INFENKDFLH IKEKYNNDWW IGRLVKEGAD ITFIPSPVKL
EAMRIKQEQK AAARKGGNAS SGGWRSTPPS TEHVPPYDVV PSMRPVVLVG PSLKGYEVTD
MMQKALFDFL KHRFDGRISI TRVTADLSLA KRSVLNKKAI MERSNTRSSL AEVQSEIERI
FELAKSLQLV VLDADTINHP AQLLKTSLAP IIVYVKVSSP KVLQRLIKSR GKSQSKHLNV
QMMAGDKLAQ CPPEMFDVIL DENQLDDACE HLAEYLEIYW RATHLPCSAP VNPVLDQSVI
TPPSANSSQQ VSFDKKSSCL SQKEQSVTTE KKRKVGYLEE EKHEEEEEQE DGGGRSDQHH
LTAAPSTTAP CSHCRATTQG RFLQLHVRW
//
