ID A0A3P8UQC9_CYNSE Unreviewed; 744 AA.
AC A0A3P8UQC9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=NCK interacting protein with SH3 domain {ECO:0000313|Ensembl:ENSCSEP00000002906.1};
GN Name=NCKIPSD {ECO:0000313|Ensembl:ENSCSEP00000002906.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000002906.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000002906.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000002906.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_008318058.1; XM_008319836.2.
DR AlphaFoldDB; A0A3P8UQC9; -.
DR STRING; 244447.ENSCSEP00000002906; -.
DR Ensembl; ENSCSET00000002950.1; ENSCSEP00000002906.1; ENSCSEG00000001916.1.
DR GeneID; 103385836; -.
DR KEGG; csem:103385836; -.
DR CTD; 51517; -.
DR GeneTree; ENSGT00390000015725; -.
DR InParanoid; A0A3P8UQC9; -.
DR OMA; CFARIFC; -.
DR OrthoDB; 2915651at2759; -.
DR Proteomes; UP000265120; Chromosome 11.
DR CDD; cd11849; SH3_SPIN90; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR030125; SPIN90/Ldb17.
DR InterPro; IPR018556; SPIN90/Ldb17_LRD.
DR InterPro; IPR035514; SPIN90_SH3.
DR PANTHER; PTHR13357:SF1; NCK-INTERACTING PROTEIN WITH SH3 DOMAIN; 1.
DR PANTHER; PTHR13357; SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF09431; SPIN90_LRD; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..58
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 102..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..289
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 744 AA; 82726 MW; E3C76E2C909ADCC7 CRC64;
MYRSLYAFRS AEPNSMHFAA GESFLILERS NKHWWLGSRC SSGETGYIPA SYIEKIQVTE
QDEVLQSIDR AIEGIHNVAL KNGGKYNLEQ RDVLQKLIHH RKETLTRRSS SSSSSLSNHK
QGIPSSNSEI SLSHTPPPPP NGLNREYGRQ GSMPSSGSMD NMQGEQPGFY QVPPQPRRAA
PITPPPPEKQ RKGQQAEPEV PSRTSSLPPS PAPSLSISST SLESGSSRSV LSSDVSLPSV
SSTPPPPVPS RVKCSVPPQD TLPSESPPPP TAFAKKSPAP QPPQLTPTPT PKSTEDSQSE
SEWPAAPLMV AESPPGSLTS SEPVPTTIGA ELIELVRKNT GLSYELSRVA VGVVVGHLQT
ALPQASSALE QVLLSLVESK DSGSALPRGQ VCHDEQRLEV IFSDLARHRD DSQQRSWALH
EDHAVIACYL EELLKILTDA DPEVCKKMCK TNHHESVLSL VSYYQMEHRV SLRLLLLKVF
GAMCSLDAAL ISTLLNSILP MELARDLQTD IQEHQKMCYT ALVLTMIFSM GEQVPYRHYE
HLNADFVQFL LDVVEDGHPS DPTEQLPDIF LNLLLSFNLH HTTPSNNVIM EELKKKNVKV
LSEKVLLLLN RGDDPVCMFN HTPPAPHSVL KFLQDLFASR ETADIFYRTD MMVMIDIAVR
QISDLSPGDK LRMEYLSLMH SIMRSTDYLE HQHRLSDLRS TLQRILREEE DPGEDEGSAT
AKQMDKLIVQ QIYKEFPQIS ENQH
//
