ID A0A3P8UQG9_CYNSE Unreviewed; 1928 AA.
AC A0A3P8UQG9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Myosin-10-like {ECO:0000313|Ensembl:ENSCSEP00000005428.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000005428.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000005428.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000005428.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR STRING; 244447.ENSCSEP00000005428; -.
DR Ensembl; ENSCSET00000005487.1; ENSCSEP00000005428.1; ENSCSEG00000003501.1.
DR GeneTree; ENSGT00940000158808; -.
DR InParanoid; A0A3P8UQG9; -.
DR OMA; MDSVAIM; -.
DR Proteomes; UP000265120; Chromosome 13.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd14920; MYSc_Myh10; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 3.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.10.250.2420; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF76; MYOSIN-10 ISOFORM X1; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 2.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 42..92
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 96..807
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..707
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1151..1170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1340..1359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1545..1581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1648..1669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1826..1852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1878..1928
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 871..1071
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1826..1851
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 189..196
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1928 AA; 222548 MW; 6AF457D0D30DBFB6 CRC64;
MSRSSGGGVN EATRLLTSGV APGSPNTNAN FKFSAASQAD WAAKRLVWVP SEKHGFESAS
IREERGDEVE VELTESQRKL TLSREEVQRM NPPRFSKVED MADLTCLNEA SVLHNLRERY
YSGLIYTYSG LFCVVVNPYK NLPIYTESIV EMYRGKKRHE MPPHIYAISE AAYRSMLQDR
EDQAILCTGE SGAGKTENTK KVIQYLAHVA SSHKGGTCGV GVDPVSRCVF QGELERQLLQ
ANPILEAFGN AKTTKNDNSS RFGKFIRINF DVAGYIVGAN IETYLLEKSR ATRQAKDERT
FHIFYQLLCG ASDETRGDLL LGTADEYRFL SGGSIHVPGQ SDSENFTQTM DSMVIMGFTP
EESLSMLKVI SAVLQFGNIS FMKEKNHDQA SMPDNTAAQK VCHLLGINVL EFTRAILTPR
IKVGREYVQK AQTKEQADFA VEALAKATYE RLFRWLVHRI NRALDRRQRQ GASFIGILDI
AGFEIFQLNS FEQLCINYTN EKLQQLFNHT MFILEQEEYQ REGIEWNFID FGLDLQPCID
LIERPAQPPG VLALLDEECW FPRATDRSFV EKLSVEQGSH PKFFKSKQPR GEADFSIIHY
AGKVDYKADK WLVKNMDPLN DNVASLLHQS SDHFVSELWK EGELIVGLDQ VSSGDSSAPV
AFGAAGLKTK KGMFRTVSQL YKESLTKLMA TLKNTNPNFL RCIIPNHEKR SGKLSPHLVL
DQLKCNGVLE GIRICRQGFP NRIPFQEFRQ RYEILTPNAI PRTFMDGKQA SELMIRALEL
DQNLYRVGQS KVFFRTGVLA HLEEERDLKI TDTIIRFQSA ARGYLARKAF LKKQQQLGAL
RVMQRNCAAY LKLRNWQWWR LFIKVKPLLQ VTRQDEEIQV RETELQKAKD QLTRAEQDYS
ELDKKHAQLV EEKAVLADQL QAEAELFAEA EEMRARLASR KQELEEVLGE LETRLEEEEE
RGVQLTNEKK RMQQNIQDLE EQLEEEESSR QRLLLEKVTL XXXXXXXXXX XTVEQRDRLS
KEKKQLEERL SEVTDQLTEE EEKTKSLNKL KNKQEAVIAD LEDRLKREEQ VRSEQEKWKR
RMETESVDTQ EQLSDLGVLV GELRGSMTQK EKEITTLQGR LEEEGAQRAE AQRSLREALS
QVSELKEEVE NERGMRERAE KQRRDLGEEL EALRTELEDT LDTTAAQQEL RSRREAELGD
LQRRIEDETR RHETQLSELR IKHTAALDNL QEQLDNSKRV RVTRPYLDTL SLTLMYLFSL
QELLQDETRQ KMALASRVRA LEEERNGLME RLEEEEEKAK ELTRQIQTHT QQLAEVRKQS
EEVNTAVEAG EEVRRKLQRE LDNSLQREQQ KEEEKDRVER QRERLREEIE DMTLALQKER
QNCMALEKRQ KKFDQCLAEE KAVSARMAEE KDKAEADSRE KDTKYLSLSR ALQEVQDQKE
ELERANKQLR FEMEQLVNQQ DDVGKNVHEL ERTRRSLEAE AQNLRVQTQE LEEELTEAEN
CRLRLEVTLQ ALKAQFEREI SSKEEKGEEK RRALSKQVRE LEIQLEEERS QRSQAMSAKK
QMEAELEDAQ AQVESSSRGK EDTLKHLRRL QAQMKEVLRE LEEAKLTRDE VISQSKDSDK
KLQSLETEVL QLTEVCVSGH KRQAKQERDE LADEIVNSST GKNAIGEEKR RLEARVSQLE
EELEEEQTNA ELLAERQRKS VLQVETLTVQ LQGERTLAQK AEAAREHLER QNKELKTRLG
EMEGAVRGKH RLGVAALEAK IDSMEEQLEQ ERQERAIANK LVRKTEKKLK EVMMQAEDER
RHADQYREQL DKSMVRLKQL KRQLEEVEEE NSRSNAQKRK LQRELEELTD NSQTMTREIS
CLRTQLRRAP LPLAMRGRRA LVDDFLENSD SEAPPASPSP SSGLPGTPTP SSDHSLDPPP
PYSVNNTE
//
